During my undergraduate degree in Biomedicine at the University of Newcastle, I first came in contact with the fascinating topic of regenerative medicine. In order to pursue this scientific interest I continued with my research with a Masters by research in stem cells and regenerative medicine at Newcastle. During that time I fist encountered Mesenchymal Stem Cell derived Extracellular Vesicles with Dr Xiao Nong Wang.
In October 2018 I joined the Division of Trauma and Orthopaedic Surgery as a PhD student working on bone marrow derived Mesenchymal Stem Cells and their extracellular vesicles.
Hotham WE, Henson FMD. The use of large animals to facilitate the process of MSC going from laboratory to patient-‘bench to bedside’. Cell Biology and Toxicology. 2020 Mar 23 [Epub]
Hotham WE, Malviya A. A systematic review of surgical methods to restore articular cartilage in the hip. Bone Joint Res. 2018 May; 7(5): 336–342.
Leitch AC, Lakey AF, W.E.Hotham, Agius L, Kass GEN, Blain PG, Wright MC. The ionic liquid 1-octyl-3-methylimidazolium (M8OI) is an activator of the human estrogen receptor alpha. Biochem Biophys Res Commun. 2018 Sep 10;503(3):2167-2172.