Rosetrees Trust Clinical Research Fellow
Biography/ Research interests
Tom Adams is a Rosetrees Trust Clinical Research Fellow, working under Prof Michael Nicholson. He is also the Geoffrey Fisk scholar at Darwin College, and an Undergraduate Clinical Supervisor at Kings College and Trinity Hall.
His current PhD research is examining regional kidney perfusion and oxygenation during normothermic machine perfusion (NMP). The aims are to improve our understanding of how different areas of the kidney are affected during transplant reperfusion, and how best to use NMP to minimise reperfusion injury.
Tom read Medicine and Physiology at University College London, where he developed interests in how humans respond to extremes of illness, endurance and environment. Prior to completing foundation medical rotations, Tom was a research fellow with the UCL Centre for Space, Altitude and Extreme Environment Medicine, during which he was deputy research lead on the largest medical expedition to Mount Everest.
Key publications
Hosgood, S. A., Moore, T., Qurashi, M., Adams, T. & Nicholson, M. L. Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. Artif Organs (2018)
Hosgood, S. A., Moore, T., Kleverlaan, T., Adams, T. & Nicholson, M. L. Haemoadsorption reduces the inflammatory response and improves blood flow during ex vivo renal perfusion in an experimental model. J Transl Med 15, 216 (2017)
Smith, S. F., Adams, T., Hosgood, S. A. & Nicholson, M. L. The administration of argon during ex vivo normothermic perfusion in an experimental model of kidney ischemia-reperfusion injury. J. Surg. Res. 218, 202–208 (2017)
Adams, T. D., Patel, M., Hosgood, S. A. & Nicholson, M. L. Lowering Perfusate Temperature From 37°C to 32°C Diminishes Function in a Porcine Model of Ex Vivo Kidney Perfusion. Transplant Direct 3, (2017)
Gilbert-Kawai, E., Sheperdigian A.A., Adams T.D. et al. Design and conduct of Xtreme Everest 2: An observational cohort study of Sherpa and lowlander responses to graduated hypobaric hypoxia. F1000Res 4, (2015)
Adams, T., Stacey, E., Stacey, S. & Martin, D. Exertional heat stroke. Br J Hosp Med (Lond) 73, 72–78 (2012)
Adams, T., Shahabi, G., Hoh-Kam, J. & Jeffery, G. Held under arrest: Many mature albino RPE cells display polyploidal features consistent with abnormal cell cycle retention. Exp Eye Res 90, 368–372 (2010)
