Senior Research Associate, Division of Trauma and Orthopaedic Surgery
I am Safety Officer for the Department Of Surgery.
I am involved in the management of tissue for research within the Division of Trauma & Orthopaedic Surgery.
Research interests include altered joint loading, subchondral bone and the osteophyte in osteoarthritis.
Steinberg J, Brooks RA, Southam L, Bhatnagar S, Roumeliotis TI, Hatzikotoulas K, Zengini E, Wilkinson JM, Choudhary JS, McCaskie AW, Zeggini E. (2018) Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology (Oxford). 2018 Aug 1;57(8):1481-1489
Steinberg J, Ritchie GRS, Roumeliotis TI, Jayasuriya RL, Clark MJ, Brooks RA, Binch ALA, Shah KM, Coyle R, Pardo M, Le Maitre CL, Ramos YFM, Nelissen RGHH, Meulenbelt I, McCaskie AW, Choudhary JS, Wilkinson JM, Zeggini E. Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis. Sci Rep. 2017 Aug 21;7(1):8935.
Varley MC, Markaki AE, Brooks RA. (2017) Effect of Rotation on Scaffold Motion and Cell Growth in Rotating Bioreactors. Tissue Eng Part A. 2017 Jun;23(11-12):522-534. doi: 10.1089/ten.TEA.2016.0357. Epub 2017 Feb 22.
Justin AW, Brooks RA, Markaki AE. (2017) Multi-casting approach for vascular networks in cellularized hydrogels. J R Soc Interface. 2016 Dec;13(125). pii: 20160768
Bennett SM, Arumugam M, Wilberforce S, Enea D, Rushton N, Zhang XC, Best SM, Cameron RC, Brooks RA (2016) The effect of particle size on the in vivo degradation of poly(d,l-lactide-co-glycolide)/α-tricalcium phosphate micro- and nanocomposites. Acta Biomater. In press.
Pawelec KM, Shepherd J, Jugdaohsingh R, Best SM, Cameron RE, Brooks RA (2015) Collagen scaffolds as a tool for understanding the biological effect of silicates. Materials Letters 157:176–179.
Ying Chow W, Rajan R, Muller KH, Reid DG, Skepper JN, Wong WC, Brooks RA, Green M, Bihan D, Farndale RW, Slatter DA, Shanahan CM, Duer MJ. (2014) NMR spectroscopy of native in vitro tissues implicates polyADP ribose in biomineralisation. Science. 344(6185): 742-6.
Areas of expertise
cell culture, immunohistochemistry, histology, tissue engineering, biomaterial science, bone tissue, cartilage tissue