2021
Davies BM, Rawal J, Hull P, Carrothers AD, et al. Major trauma care at a regional trauma centre during the COVID-19 lockdown in England. Annals of The Royal College of Surgeons of England. 2021 December.
Gnanapragasam V, Barrett T, Berry B, Richoz N, et al. Resolving the immune landscape of human prostate at a single-cell level in health and cancer. Cell Reports. 2021 December 21. Volume 37, Issue 12.
Hosgood S, Nicholson ML, Ferdinand J, Bates L, et al. MicroRNA antagonist therapy during normothermic machine perfusion of donor kidneys. American Journal of Transplantation. 2021 December 21.
Elliott TR, Hosgood S, Nicholson ML, Kosmoliaptsis V, Ashcroft J, Leighton P. Extracellular Vesicles in Kidney Transplantation: A State of the Art Review. Kidney International. 2021 November 26.
Vallier L, Tyser RCV, Mahammadov E, Nakanoh S, Scialdone A, Srinivas S. Single-cell transcriptomic characterization of a gastrulating human embryo. Nature. 2021 November 17.
Stewart GD, Grayling MJ, Mossop H, Gallagher FA, Welsh SJ, Wason JMS. Advantages of multi-arm non-randomised sequentially allocated cohort designs for Phase II oncology trials. British Journal of Cancer. 2021 November 08.
Stewart GD, Zhou Y, Walter F, Abel G, Hamilton W, et al. Identifying opportunities for timely diagnosis through patterns of primary care tests in patients with bladder and renal cancer: a longitudinal linked data study. British Journal of General Practice. 2021 October 20.
Davies BM, Hull P, Ghobrial M, Hussain A, Carrothers AD, Rawal J, Chou D. 1085 Equestrian Related Pelvic and Acetabular Fractures – Experience from a Major Trauma Centre in England. British Journal of Surgery. 2021 October 12. Volume 108, Issue Supplement_6.
Chowdhury MM, Le E, Rudd JH, Tarkin J, Evans N. 875 Using Stress Testing to Identify Vulnerabilities in Artificial Intelligence Models for the Identification of Culprit Carotid Lesions in Cerebrovascular Events. British Journal of Surgery. 2021 October 12. Volume 108, Issue Supplement_6.
Stewart GD, Dabestani S, Fossati N, Järvinen P, et al. Impact of surgical approach (open vs. minimally invasive) on oncological outcomes after nephrectomy for localised renal cell carcinoma: a recur database project. European Urology Open Science. 2021 October. 32:S149-S150. [Online ahead of print].
Kosmoliaptsis V, Gillett D, Bashari WA, Aloj L, Brown M, et al. [ 11 C]Metomidate PET/CT can aid decision-making in patients with primary aldosteronism. Endocrine Abstracts. 2021 October.
Chakrabarti S, Ai M, Henson FMD, St. John Smith E, Wong K, Newell K. Functional characterization of ovine dorsal root ganglion neurons reveal peripheral sensitization after osteochondral defect. eNeuro. 2021 September 20. 0237-21.2021.
Richards J, Memba R, Pavel MC, et al. Should local rather than national policy determine our approach to surgery during SARS-CoV-2?. Journal of Gastroenterology and Hepatology Research. 2021 September.
Vallier L, Muraro D, Brumm SA, Niakan KK, et al. TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells. eLife Sciences 10. 2021 August 31.
Gamble J, Mahbubani K, Saeb-Parsy K, Fitzgerald RC, Nowicki-Osuch K, O’Donovan M, et al. Molecular phenotyping reveals the identity of Barrett’s esophagus and its malignant transition. Science. 2021 August 13. Vol. 373, Issue 6556, pp. 760-767.
Chowdhury MM, Chen X, Sofat S, Coughlin P. Effects of Statin Therapy and Dose on Cardiovascular and Limb Outcomes in Peripheral Arterial Disease: A Systematic Review and Meta-analysis. European Journal of Vascular and Endovascular Surgery. 2021 August 10.
Vallier L, Tilson SG, Morell MM, Lenaerts A-S, Park SB, Hu Z, Jenkins B, Koulman A, Liang TJ. Modelling PNPLA3‐Associated Non‐Alcoholic Fatty Liver Disease Using Human Induced Pluripotent Stem Cells. Hepatology. 2021 Jul 20.
Copley CC, Gragert L, Kosmoliaptsis V, Leach AR. Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual Level. Frontiers in Immunology. 2021 Jul 19. 12:669357.
Gnanapragasam V, Sushentsev N, Rundo L, Blyuss O, Nazarenko T, Suvorov A, Sala E, Barrett T. Comparative performance of MRI-derived PRECISE scores and delta-radiomics models for the prediction of prostate cancer progression in patients on active surveillance. European Radiology. 2021 Jul 13.
Wilson ECF, Wreford A, Tamer P, Leonard K, Brechka H, Gnanapragasam V. Economic Evaluation of Transperineal versus Transrectal Devices for Local Anaesthetic Prostate Biopsies. PharmacoEconomics – Open. 2021 Jul 09.
Thurtle D, Jenkins V, Freeman A, Pearson M, Recchia G, Tamer P, Leonard K, Gnanapragasam V. et al. Clinical impact of the predict prostate risk communication tool in men newly diagnosed with non-metastatic prostate cancer: A multi-centre randomised controlled trial. European Urology. 2021 Jul 08. Pages S1446-S1447. [Online ahead of print].
Light A, Keates A, Thankappannair V, Warren A, Barrett T, Gnanapragasam V. Development of the STRATified CANcer Surveillance protocol for men with favourable-risk prostate cancer. European Urology. 2021 Jul 08. Pages S1473-S1474. [Online ahead of print].
Tambur AR, Kosmoliaptsis V, Claas FHJ, Mannon RB, Nickerson P, Naesens M. Significance of HLA-DQ in kidney transplantation – Time to re-evaluate HLA matching priorities to improve transplant outcomes? An expert review and recommendations. Kidney International Reports. 2021 Jul 08. [Online ahead of print].
Loh B, Lim JA, Seah M, Khan WS. Perioperative management of open fractures in the lower limb. Journal of Perioperative Practice 2021 Jul 02 PMID: 34214004.
Sushentsev N, Rundo L, Blyuss O, Gnanapragasam VJ, Sala E, Barrett T. MRI-derived radiomics model for baseline prediction of prostate cancer progression on active surveillance. Scientific Reports 2021 Jun 21. Article number: 12917.
Richards JA, Roberts JL, Fedotovs A, Paul S, Cottee S, Defries G, Watson CJE, Pettigrew GJ. Outcomes for circulatory death and brainstem death pancreas transplantation with or without use of normothermic regional perfusion. British Journal of Surgery 2021 Jun 22.
Jochmans I, Hessheimer AJ, Neyrinck AP, Watson CJE. et al. Consensus statement on normothermic regional perfusion in donation after circulatory death: report from the European Society for Organ Transplantation’s Transplant Learning Journey. Transpl. Int. 2021 Jun 18. [Online ahead of print].
Byrne MHV, Mehmood A, Summers DM, Hosgood SA, Nicholson ML. A systematic review of living kidney donor enhanced recovery after surgery. Clinical Transplantation. 2021 Jun 08. e14384.
Carter AR, Davies BM, Brindley DA. Gazing Long into a Clinical and Social Abyss? Treating Hypertrophic Scarring and Keloids. Rejuvenation Research 2021 Jun 08. Volume 24, Number 4
Eldridge SE, Barawi A, Roelofs A, Henson FMD, De Bari C, McCaskie AW, et al. AB0039 Agrin repairs bone and cartilage in vivo. Annals of the Rheumatic Diseases. 2021 June 80(Suppl 1):1052.1-1052.
Blackmur JP, Gaba F, Fernando D, Williams S, Stewart GD. et al. Leibovich score is the optimal clinico-pathological system associated with recurrence of non-metastatic clear cell renal cell carcinoma. Urol. Oncol. 2021 May 19;S1078-1439(21)00164-2.
Light A, Burns-Cox N, Maccormick A, John J, McGrath J, Gnanapragasam VJ. The diagnostic impact of UK regional variations in age-specific prostate-specific antigen guidelines. BJU Int. 2021 May 20.
Waseem S, Lenihan J, Davies BM, Rawal J, Hull P, Carrothers A, Chou D. Low Body Mass Index is Associated with Increased Mortality in Patients with Pelvic and Acetabular Fractures. Injury Reports. 2021 May 04. [Online ahead of print]
Dolezalova N, Gruszczyk A, Barkan K, Gamble JA, Mahbubani KT, Higgins JA, Saeb-Parsy K, et al. Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets. Sc Rep. 2021 May 17;11(1):10418.
Kamaraj A, Agarwal N, Agarwal, Seah KTM, Khan WS. Understanding cost-utility analysis studies in the trauma and orthopaedic surgery literature. EFORT Open Reviews 2021 May;6(5)
Corrie PG, Welsh SJ, Stewart GD, et al. Identification of a microbiome signature predicting immune checkpoint inhibitor outcomes across multiple cancer types in the MITRE study. Journal of Clinical Oncology 2021 May; 39(15_suppl):TPS2665-TPS2665
Dokubo II, Reeves F, Cashman S, Gnanapragasam VJ. Rationalising the use of investigation for urinary tract infections: Analysis of 700 patients and proposal for a diagnostic algorithm. Int J Clin Pract. 2021 May;75(5):e13977.
Steinberg J, Southam L, Fontalis A, Clark MJ, Jayasuriya RL, Swift D, Shah KM, Brooks RA, McCaskie AW, Wilkinson JM, Zeggini E. Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis. Ann Rheum Dis. 2021 Apr 26;annrheumdis-2020-219760 [Online ahead of print]
Greenhall GHB, Robb M, Brown C, Johnson R, Tomlinson LA, Callaghan CJ, Watson CJE. Solid Organ Transplantation From Deceased Donors With Infective Endocarditis: The UK Experience. Transplantation. 2021 Apr 21. [Online ahead of print]
Abu-Ghanem Y, Powles T, Capitanio U, Beisland C, Järvinen P, Stewart GD et al. Should patients with low risk renal cell carcinoma be followed differently after nephron‐sparing surgery vs radical nephrectomy? BJU Int. 2021 Apr 1. [Online ahead of print]
Sokal DM, McSloy A, Donegà M, Kirk J, Colas RA, Dolezalova N et al. Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs. Front Immunol. 2021 Mar 29;12:649786.
COVIDSurg Collaborative (incl G.D. Stewart). SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg. 2021 Mar 24;znab101. [Online ahead of print]
Van Hemelrijck M, Ji X, Helleman J, Roobol MJ, Gnanapragasam V et al. A first step towards a global nomogram to predict disease progression for men on active surveillance. Transl Androl Urol. 2021 Mar;10(3):1102-1109.
COVIDSurg Collaborative (incl G.D. Stewart, dissemination committee). Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia. 2021 Mar 9. [Online ahead of print]
Lee C, Light A, Alaa A, Thurtle D, van der Schaar M, Gnanapragasam VJ. Application of a novel machine learning framework for predicting non-metastatic prostate cancer-specific mortality in men using the Surveillance, Epidemiology, and End Results (SEER) database. Lancet Digit Health. 2021 Mar;3(3):e158-e165.
Liu S, Shen M, Hsu EC, Zhang CA, Garcia-Marques F, Gnanapragasam VJ, Stoyanova T et al. Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer. Br J Cancer. 2021 Mar;124(5):896-900.
Sutton E, Lane JA, Davis M, Walsh EI, Neal DE, Hamdy FC, Mason M, Staffurth J, Martin RM, Metcalfe C, Peters TJ, Donovan JL, Wade J; ProtecT Study Group (Gnanapragsam VJ). Men’s experiences of radiotherapy treatment for localized prostate cancer and its long-term treatment side effects: a longitudinal qualitative study. Cancer Causes Control. 2021 Mar;32(3):261-269.
COVIDSurg Collaborative (incl G.D. Stewart, writing group). Elective cancer surgery in COVID-19 free surgical pathways during the SARS-CoV-2 pandemic: An international, multi-centre, comparative cohort study. Journal of Clinical Oncology. 2021;39(1):66-78.
Steinberg J, Southam L, Roumeliotis TI, Brooks RA, McCaskie AW et al. Nature Commun. 2021 Feb 26;12(1):1309.
Kuusk T, Klatte T, Stewart GD, et al. Outcome after resection of occult and non-occult lymph node metastases at the time of nephrectomy. World J Urol. 2021 Feb 25. [Online ahead of print]
Bruinsma SM, Nieboer D, Gnanapragasam V, et al. Risk-Based Selection for Active Surveillance: Results of the Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance (GAP3) Initiative. J Urol. 2021 Feb 22;101097JU0000000000001700. [Online ahead of print]
Anderton J, Ghobrial M, Kosmoliaptsis V, Casey R. Large adrenal mass heralding the diagnosis of occult extra-adrenal malignancy in two patients. BMJ Case Rep. 2021 Feb 22;14(2):e239463.
MacKay JW, Nezhad FS, Rifai T, Kaggie JD, Naish JH, Roberts C, Graves MJ, Waterton JC, Janiczek RL, Roberts AR, McCaskie A, Gilbert FJ, Parker GJM. Dynamic contrast-enhanced MRI of synovitis in knee osteoarthritis: repeatability, discrimination and sensitivity to change in a prospective experimental study. Eur Radiol. 2021 Feb 16. [Online ahead of print]
Ecke TH, Schwaiger D, Nesterov G, Koswig S, Selinski S, Barrett T, Gnanapragasam V et al . Comparison of initial and second opinion reads of multiparametric magnetic resonance imaging of the prostate for transperineal template-guided biopsies with MRI-Ultrasound fusion. Urol Oncol. 2021 Feb 6:S1078-1439(21)00007-7.
Richards JA, Gaurav R, Upponi SS, Watson CJE, Butler AJ. Machine Perfusion-Leaving Its Mark on Liver Transplantation. Transplantation 2021 Feb 1;105(2):e28-e29.
Stewart GD, Welsh S, Ursprung S, et al. NAXIVA: A phase II neoadjuvant study of axitinib for reducing extent of venous tumor thrombus in clear cell renal cell cancer (RCC) with venous invasion. Journal of Clinical Oncology. 2021 Feb. 39(6_suppl):275-275
Agarwal N, To K, Khan WS. Cost effectiveness analyses of total hip arthroplasty for hip osteoarthritis: A PRISMA systematic review. Int J Clin Pract. 2021 Feb;75(2):e13806
Chan CD, Haagensen EJ, Tensaout HA, Rennie KJ, Gamie Z, Barry J, Birch MA, Gerrand CH. Co localisation of intra nuclear membrane type 1 matrix metalloproteinase and hypoxia inducible factor 2α in osteosarcoma and prostate carcinoma cells. Oncology Letters. 2021 21(2):1–1.
Richards JA, Randle LV, Butler AJ, Martin JL, Fedotovs A, Davies SE, Watson CJE, Robertson PA. Clinical trial of a real-time optical backscatter probe predicts liver transplantation outcomes. Transpl. Int 2021 Jan 19. [Online ahead of print]
Richards J, Gimson A, Joh Y, Watson C, Neuberger J. Trials & Tribulations of Liver Transplantation- are trials now prohibitive without surrogate endpoints? Liver transpl. 2021 Jan 19. [Online ahead of print]
Tomlinson F, Terschuur J, Henson FMD. Use of autologous products for the treatment of joint and soft tissue disease in horses: A systematic review. The Veterinary record. 2021 Jan; 188(2)
2020
Bottle A, Griffiths R, White S, Davies BM, et al. Periprosthetic fractures: the next fragility fracture epidemic? A national observational study. BMJ Open. 2020 Dec 10;10(12):e042371.
Eisen T, Frangou E, Oza B, Stewart GD, et al. Adjuvant Sorafenib for Renal Cell Carcinoma at Intermediate or High Risk of Relapse: Results From the SORCE Randomized Phase III Intergroup Trial. J. Clin. Oncol. 2020 Dec 1;38(34):4064-4075.
Sushentsev N, Kaggie JD, Buonincontri G, Schulte RF, Graves MJ, Gnanapragasam VJ, Barrett T. The effect of gadolinium-based contrast agent administration on magnetic resonance fingerprinting-based T 1 relaxometry in patients with prostate cancer. Sci Rep. 2020 Nov 24;10(1):20475.
Caglic I, Sushentsev N, Gnanapragasam VJ, et al. MRI-derived PRECISE scores for predicting pathologically-confirmed radiological progression in prostate cancer patients on active surveillance. Our Radiol. 2020 Nov 16. [Online ahead of print]
Henson F, Lydon H, Birch M, Brooks R, McCaskie A. Using apheresis-derived cells to augment microdrilling in the treatment of chondral defects in an ovine model. J Orthop Res. 2020 Nov 4. [Online ahead of print]
Matas‐Céspedes A, Brown L, Mahbubani K, Saeb-Parsy K et al. Use of human splenocytes in an innovative humanised mouse model for prediction of immunotherapy‐induced cytokine release syndrome. Clinical & Translational Immunology. 2020 Nov 4; 9(e1202)
Henson F, Lydon H, Birch MA, Brooks R, McCaskie AW. Using apheresis-derived cells to augment microdrilling in the treatment of chondral defects in an ovine model. Journal of Orthopaedic Research 2020 Nov 4. [Online ahead of print]
Agarwal N, To K, Mcdonnell S, Khan WS. Clinical and radiological outcomes in robotic assisted total knee arthroplasty: a systematic review and meta-analysis. Journal of Arthroplasty Volume 35, Issue 11, November 2020, Pages 3393-3409.e2.
Gupta I, Cassará AM, Tarotin I, Donega M, Dolezalova N, Saeb-Parsy K, et al. Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves. Commun Biol. 2020 Oct 16;3(1):577.
Kamaraj A, To K, Seah M, Khan WS. Modelling the cost-effectiveness of total knee arthroplasty: A systematic review. J Ortho. 2020 Oct 8;22:485-492.
Cunniffe NG, Gunter SJ, Brown M, Stewart GD, et al. How achievable are COVID-19 clinical trial recruitment targets? A UK observational cohort study and trials registry analysis. BMJ Open 2020 Oct 5;10(10):e044566.
Lawson ARJ, Abascal F, Mahbubani KT, Bareham B, Gnanapragasam V, Saeb-Parsy K, Mitchell T, et al. Extensive heterogeneity in somatic mutation and selection in the human bladder. Science. 2020 Oct 2;Vol. 370, Issue 6512, pp. 75-82.
Guldvik IJ, Zuber V, Braadland PR, Gnanapragasam V, et al. Identification and Validation of Leucine-rich a-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification. European Urology Open Science. 2020 Oct; Vol.21:51-60
Atici SD, Kaya T, Aydin C, Stewart GD, et al. Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic. British Journal of Surgery 2020 Oct
Litviňuková M, Talavera-López C, Maatz H, Saeb-Parsy K, Mahbubani KT, et al. Cells of the adult human heart. Nature. 2020 Sep 24. [Online ahead of print]
Jordan NP, Nicholson ML, Hosgood SA. MicroRNA-126-3p is Downregulated in Human Kidneys in a Model of Reperfusion Injury. Kidney International Reports. 2020 Sep 23;5(12) P2357-2360.
Saeb-Parsy K, Martin JL, Summers DM, Watson CJE, Krieg T, Murphy MP. Mitochondria as Therapeutic Targets in Transplantation. Trends Mol Med. 2020 Sep 17;S1471-4914(20)30190-8. [Online ahead of print]
Mostafa AMHAM, Kyriacou H, Chimutengwende-Gordon M, Khan WS. An overview of the key principles and guidelines in the management of pelvic fractures. J Perioper Pract. 2020 Sep 8;1750458920947358.
Lim JA, Loh B, Sylvestor G, Khan W. Perioperative management of distal radius fractures. J Perioper Pract. 2020 Sep 8;1750458920949463. [Online ahead of print]
Eldridge SE, Barawi A, Wang H, Roelofs A, Henson F, McCaskie AM, De Bari C, et al. Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis. Science Translational Medicine. 2020 Sep 2;12(559) eaax9086
Crispin-Ortuzar M, Gehrung M, Ursprung S, Stewart G, Mitchell T, et al. Three-Dimensional Printed Molds for Image-Guided Surgical Biopsies: An Open Source Computational Platform Licensed under the Creative Commons Attribution 4.0 License. JCO Clinical Cancer Informatics. August 2020; 4(4):736-748
Seefried L, Blyth M, Maheshwari R, McDonnell SM, et al. Penetration of topical diclofenac into synovial tissue and fluid of osteoarthritic knees: a multicenter, randomized, placebo-controlled, pharmacokinetic study. Ther Adv Musculoskelet Dis. 2020 Aug 29;12:1759720X20943088. eCollection 2020.
Usher-Smith J, Simmons RK, Rossi S, Stewart GD. Current evidence on screening for renal cancer. Nature Reviews Urology. 2020 Aug 28 [online]
Darst BF, Dadaev T, Saunders EJ, Gnanapragasam VJ et al. Germline sequencing DNA repair genes in 5,545 men with aggressive and non-aggressive prostate cancer. J Natl Cancer Inst. 2020 Aug 27;djaa132. [Online ahead of print]
Prag HA, Gruszczyk AV, Huang MM, Beach TE, Saeb-Parsy K et al. Mechanism of succinate efflux upon reperfusion of the ischemic heart. Cardiovasc Research. 2020 Aug 7;cvaa148. [Online ahead of print]
Chakrabarti S, Ai M, Henson FMD, St. John Smith E. Peripheral mechanisms of arthritic pain: A proposal to leverage large animals for in vitro studies. Neurobiology of Pain. 2020 July 28. [Epub]
Noble S, Garfield K, Gnanapragasam VJ et al. The ProtecT randomised trial cost-effectiveness analysis comparing active monitoring, surgery, or radiotherapy for prostate cancer. Br J Cancer. 2020 Jul 16 [Epub ahead of print]
Harrison H, Thompson RE, Lin Z, Rossi SH, Stewart GD, Griffin SJ, Usher-Smith JA. Risk Prediction Models for Kidney Cancer: A Systematic Review. Eur Urol Focus. 2020 Jul 14:S2405-4569(20)30190-5 [Epub ahead of print]
Prag HA, Pala L, Kula-Alwar D, Saeb-Parsy K, Beach TE, et al. Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo. Cardiovasc Drugs Ther. 2020 July 9 [Epub ahead of print]
Bentley S, Johnson C, Exall E, Brohan E, Lawrance R, Bennett B, Bargo D, Zanotti G, Staehler M, Stewart G. Improving patient-clinician communication following nephrectomy in Renal Cell Carcinoma: Development, content validation and pilot testing of a Conversation Aid Tool. Patient Education and Counseling. 2020 June 30 [online]
Ayorinde JOO, Saeb-Parsy K, Hossain A. Opportunities and Challenges in Using Social Media in Organ Donation. JAMA Surg. 2020 June 17 [online]
Wan JCM, Stewart GD et al. ctDNA Monitoring Using Patient-Specific Sequencing and Integration of Variant Reads Sci Transl Med. 2020 Jun 17;12(548):eaaz8084.
Thurtle D, Bratt Ola, Stattin P, Pharoah P, Gnanapragasam VJ. Comparative performance and external validation of the multivariable PREDICT Prostate tool for non-metastatic prostate cancer: A study in 69,206 men from Prostate Cancer data Base Sweden (PCBaSe). BMC Med. 2020 Jun 16;18(1):139.
Gnanapragasam VJ, Leonard K, Sut M, Ilie C, Ord J, Roux J, Prieto MCH, Warren A, Tamer P. Multicentre clinical evaluation of the safety and performance of a simple transperineal access system for prostate biopsies for suspected prostate cancer: The CAMbridge PROstate Biopsy DevicE (CamPROBE) study. Journal of Clinical Urology. 2020 June 12 [Epub ahead of print]
To K, Romain K, Mak C, Kamaraj A, Henson F, Khan W. The Treatment of Cartilage Damage Using Human Mesenchymal Stem Cell-Derived Extracellular Vesicles: A Systematic Review of in vivo Studies. Front Bioeng Biotechnol 2020 Jun 11;8:580. [eCollection 2020]
Zawaideh JP, Sala E, Pantelidou M, Shaida N, Koo B, Caglic I, Warren AY, Carmisciano L, Saeb-Parsy K, Gnanapragasam VJ, Kastner C, Barrett T. Comparison of Likert and PI-RADS Version 2 MRI Scoring Systems for the Detection of Clinically Significant Prostate Cancer. Radiol. 2020 Jun 1;20200298. [Epub ahead of print]
Migliorini F, Berton A, Salvatore G, Candela V, Khan WS, Longo UG, Denaro V. Autologous chondrocyte implantation and mesenchymal stem cells for the treatments of chondral defects of the knee- a systematic review. Curr Stem Cell Res Ther. 2020;15(6):547-556.
Basyuni S, Ferro A, Santhanam V, Birch MA, McCaskie AW. Systematic scoping review of mandibular bone tissue engineering. Br J Oral Maxillofac Surg . 2020 58(6) 632-642.
Parry MG, Cowling TE, Sujenthiran A, Nossiter J, Berry B, Cathcart P, Aggarwal A, Payne H, van der Meulen J, Clarke NW, Gnanapragasam VJ. Risk stratification for prostate cancer management: value of the Cambridge Prognostic Group. BMC Med. 2020 May 28;18(1):114.
Kaggie JD, Markides H, Graves MJ, MacKay J, Houston G, El Haj A, Gilbert F, Henson FMD. Ultra Short Echo Time MRI of Iron-Labelled Mesenchymal Stem Cells in an Ovine Osteochondral Defect Model. Sci Rep. 2020 May 21;10(1):8451.
Paterson YZ, Cribbs A, Espenel M, Smith EJ, Henson FMD, Guest DJ. Genome-wide transcriptome analysis reveals equine embryonic stem cell-derived tenocytes resemble fetal, not adult tenocytes. Stem Cell Research & Therapy 2020 May 19;11(184)
Green M, Byrne MHV, Legard C, Chen E, Critchley A, Stainer B, Chaggar H, Symington M, Hu L, Brathwaite-Shirley C, Mayes J, Mogg JAW, Murphy J, Saeb-Parsy K. The Effect of Positive and Negative Poster Messages on Organ Donor Registration. Transplant Proc. 2020 May 16:S0041-1345(20)30280-3.[Epub ahead of print]
Chisari E, Rehak L, Khan WS, Maffulli N. The Role of the Immune System in Tendon Healing: A Systematic Review. Br Med Bull. 2020 May 15;133(1):49-64.
Ranmuthu CDS, Ranmuthu CKI, Russell JC, Singhania D, Khan WS. Evaluating the Effect of Non-cellular Bioactive Glass-Containing Scaffolds on Osteogenesis and Angiogenesis in in vivo Animal Bone Defect Models. Front Bioeng Biotechnol. 2020 May 14;8:430.
Tambur AR, Campbell P, Chong AS, Feng S, Ford ML, Gebel H, Gill RG, Kelsoe G, Kosmoliaptsis V, Mannon RB, Mengel M, Reed EF, Valenzuela NM, Wiebe C, Dijke E, Sullivan HC, Nickerson P. Sensitization in Transplantation: Assessment of Risk (STAR) 2019 Working Group Meeting Report. Am J Transplant. 2020 Apr 27. [Epub ahead of print]
Bojanic C, To K, Zhang B, Mak C, Khan WS. Human umbilical cord derived mesenchymal stem cells in peripheral nerve regeneration. World J Stem Cells. 2020 Apr 26;12(4):288-302.
Sungnak W, Huang N, Bécavin C, Berg M, Queen R, Litvinukova M, Talavera-López C, Maatz H, Reichart D, Sampaziotis F, Worlock KB, Yoshida M, Barnes JL; HCA Lung Biological Network. SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nat Med. 2020 Apr 23. [Epub ahead of print]
Wajs E, Rughoobur G, Burling K, George A, Flewitt A, Gnanapragasam V. A novel split mode TFBAR devices for quantitative measurements of prostate specific antigen in a small sample of whole blood. Nanoscale. 2020 May 7;12(17):9647-9652. Epub 2020 Apr 22.
Moore L, Leongamornlert D, Coorens THH, Sanders MA, Ellis P, Dentro SC, Dawson KJ, Butler T, Rahbari R, Mitchell TJ, Maura F, Nangalia J, Tarpey PS, Brunner SF, Lee-Six H, Hooks Y, Moody S, Mahbubani KT, Jimenez-Linan M, Brosens JJ, Iacobuzio-Donahue CA, Martincorena I, Saeb-Parsy K, Campbell PJ, Stratton MR. The mutational landscape of normal human endometrial epithelium. Nature. 2020 Apr;580(7805):640-646. [Epub 2020 Apr 22]. press release
Kim L, Boxall N, George A, Burling K, Acher P, Aning J, McCracken S, Page T, Gnanapragasam VJ. Clinical utility and cost modelling of the phi test to triage referrals into image-based diagnostic services for suspected prostate cancer: the PRIM (Phi to RefIne Mri) study. BMC Med. (2020) IF 8.3 Apr 17;18(1):95
Kyriacou H, Khan WS. Important perioperative factors, guidelines and outcomes in the management of hip fracture. J Perioper Pract. 2020 Apr 17:1750458920915656.
Al-Lamki RS, Hudson NJ, Bradley JR, Warren AY, Eisen T, Welsh SJ, Riddick ACP, O’Mahony FC, Turnbull A, Powles T, Scotrrcc Collaborative, Reverter A, Harrison DJ, Stewart GD. The Efficacy of Sunitinib Treatment of Renal Cancer Cells Is Associated with the Protein PHAX In Vitro. Biology (Basel). 2020 Apr 7;9(4). pii: E74.
Hemelrijck MV, Ji X, Helleman J, Roobol M, Nieboer D, Bangma C, Frydenberg M, Rannikko A, Lee LS, Gnanapragasam V, Kattan M and GAP3 Movember Foundation’s Active Surveillance Database. PD62-01 A first step towards a global nomogram to predict disease progression for men on active surveillance. Journal of Urology 2020 April 1; vol.203, Issue Supplement 4
Ellis RJ, Del Vecchio SJ, Gallagher KMJ, Aliano DN, Barber N, Bolton DM, Chew ETS, Coombes JS, Coory MD, Davis ID, Donaldson JF, Francis RS, Giles GG, Gobe GC, Hawley CM, Johnson DW, Laird A, Leung S, Malki M, Marco DJT, McNeill AS, Neale RE, Ng KL, Phipps S, Stewart GD, White VM, Wood ST, Jordan SJ. A Simple Clinical Tool for Stratifying Risk of Clinically Significant CKD after Nephrectomy: Development and Multinational Validation. JASN 2020 April; ASN.2019121328
JW MacKay, TD Turmezei, J Kaggie, AR Morgan, R Janiczek, WS Khan, S McDonnell, MJ Graves. Three-dimensional Surface-based Analysis of Cartilage MRI data in Knee Osteoarthritis: Validation and Initial Clinical Application. JMRI 2020 52(4):1139-1151. PMID: 32447815
Hotham WE, Henson FMD. The use of large animals to facilitate the process of MSC going from laboratory to patient-‘bench to bedside’. Cell Biology and Toxicology. 2020 Mar 23 [Epub]
Zawaideh JP, Sala E, Shaida N. Koo B, Warren AY, Carmisciano L, Saeb-Parsy K, Gnanapragasam VJ, Kastner C, Barrett T. Diagnostic accuracy of biparametric versus multiparametric prostate MRI: assessment of contrast benefit in clinical practice. Eur Radiol 2020 March 12; [Epub]
Watson CJE, Johnson RJ, Mumford L. Overview of the Evolution of the UK Kidney Allocation Schemes. Curr Transpl Rep. 2020 March 12; [Epub]
Thomas BC, Slack M, Hussain M, Barber N, Pradhan A, Dinneen E, Stewart GD. Preclinical Evaluation of the Versius Surgical System, a New Robot-assisted Surgical Device for Use in Minimal Access Renal and Prostate Surgery. Eur Urol Focus. 2020 Mar 10. pii: S2405-4569(20)30029-8. [Epub ahead of print]
Park JE, Botting RA, Domínguez Conde C, Popescu DM, Lavaert M, Kunz DJ, Goh I, Stephenson E, Ragazzini R, Tuck E, Wilbrey-Clark A, Roberts K, Kedlian VR, Ferdinand JR, He X, Webb S, Maunder D, Vandamme N, Mahbubani KT, Polanski K, Mamanova L, Bolt L, Crossland D, de Rita F, Fuller A, Filby A, Reynolds G, Dixon D, Saeb-Parsy K, Lisgo S, Henderson D, Vento-Tormo R, Bayraktar OA, Barker RA10, Meyer KB, Saeys Y, Bonfanti P, Behjati S, Clatworthy MR, Taghon T1, Haniffa M, Teichmann SA. A cell atlas of human thymic development defines T cell repertoire formation. Science. 2020 Feb 21;367(6480). pii: eaay3224.
James KR, Gomes T, Elmentaite R, Kumar N, Gulliver EL, King HW, Stares MD, Bareham BR, Ferdinand JR, Petrova VN, Polański K, Forster SC, Jarvis LB, Suchanek O, Howlett S, James LK, Jones JL, Meyer KB, Clatworthy MR, Saeb-Parsy K, Lawley TD, Teichmann SA Distinct microbial and immune niches of the human colon. Nat Immunol. 2020 Feb 17. [Epub ahead of print]
Yong C, Stewart GD. Transcriptomic Signatures Related to the Obesity Paradox in Patients with Clear Cell Renal Cell Carcinoma: A Cohort Study. Eur Urol. 2020 Feb 12. pii: S0302-2838(20)30069-5. [Epub ahead of print]
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium. Pan-cancer analysis of whole genomes. Nature. 2020 Feb;578(7793):82-93. (Co-authors: Gnanapragasam VJ, Mitchell T.)
Kwan H, Chisari E, Khan WS. Cell-Free Scaffolds as a Monotherapy for Focal Chondral Knee Defects. Materials (Basel). 2020 13(2): E306. PMID: 31936591
Noorani A, Li X, Goddard M, Crawte J, Alexandrov LB, Secrier M, Eldridge MD, Bower L, Weaver J, Lao-Sirieix P, Martincorena I, Debiram-Beecham I, Grehan N, MacRae S, Malhotra S, Miremadi A, Thomas T, Galbraith S, Petersen L, Preston SD, Gilligan D, Hindmarsh A, Hardwick RH, Stratton MR, Wedge DC, Fitzgerald RC. Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma. Nat Genet. 2020 Jan;52(1):74-83. online aticle
Sushentsev N, Caglic I, Sala E, Shaida N, Slough RA, Carmo B, Kozlov V, Gnanapragasam V, Barrett T. The effect of capped biparametric magnetic resonance imaging slots on weekly prostate cancer imaging workload. Br J Radiol. 2020 Jan 23:20190929.[Epub ahead of print]
de Bruijn R, Wimalasingham A, Szabados B, Stewart GD, Welsh SJ, Kuusk T, Blank C, Haanen J, Klatte T, Staehler M, Powles T, Bex A. Deferred Cytoreductive Nephrectomy Following Presurgical Vascular Endothelial Growth Factor Receptor-targeted Therapy in Patients with Primary Metastatic Clear Cell Renal Cell Carcinoma: A Pooled Analysis of Prospective Trial Data. Eur Urol Oncol. 2020 Jan 16. pii: S2588-9311(20)30001-8. [Epub ahead of print]
Manara A, Shemie SD, Large S, Healey A, Baker A, Badiwala M, Berman M, Butler AJ, Chaudhury P, Dark J, Forsythe J, Freed DH, Gardiner D, Harvey D, Hornby L1, MacLean J, Messer S, Oniscu GC, Simpson C, Teitelbaum J, Torrance S, Wilson LC, Watson CJE. Maintaining the permanence principle for death during in situ normothermic regional perfusion for donation after circulatory death organ recovery: A United Kingdom and Canada proposal. Am J Transplant. 2020 Jan 10. [Epub ahead of print]
Bryant RJ, Oxley J, Young GJ, Lane JA, Metcalfe C, Davis M, Turner EL, Martin RM, Goepel JR, Varma M, Griffiths DF, Grigor K, Mayer N, Warren AY, Bhattarai S, Dormer J, Mason M, Staffurth J, Walsh E, Rosario DJ, F Catto JW, Neal DE, Donovan L, Hamdy FC; ProtecT Study Group, Bollina P, Doble A, Doherty A, Gillatt D, Gnanapragasam V, Hughes O, Kockelbergh R, Kynaston H, Paul A, Paez E, Rowe E. The ProtecT trial: analysis of the patient cohort, baseline risk stratification and disease progression. BJU Int. 2020 Jan 3.
Books and Chapters
Iyer K and Khan WS. (eds) (2020) Orthopedics of the Upper and Lower Limb. Springer, Cham.
Davies BM and Khan WS (2020) Stem Cell Therapy in Orthopedics. In: Iyer K., Khan W. (eds) Orthopedics of the Upper and Lower Limb. Springer, Cham. pp 565-572
2019
Klatte T, Stewart GD. Partial nephrectomy versus thermal ablation for clinical T1 renal tumours. Ann Transl Med 2019 Dec;7 (Suppl 8):S363.
Chisari E, Rehak L, Khan WS, Maffulli N. Tendon healing in presence of chronic low-level inflammation: a systematic review. Br Med Bull. 2019 Dec 14. pii: ldz035. [Epub ahead of print]
Coorens THH, Treger TD, Al-Saadi R, Moore L, Tran MGB, Mitchell TJ, Tugnait S, Thevanesan C, Young MD, Oliver TRW, Oostveen M, Collord G, Tarpey PS, Cagan A, Hooks Y, Brougham M, Reynolds BC, Barone G, Anderson J, Jorgensen M, Burke GAA, Visser J, Nicholson JC, Smeulders N, Mushtaq I, Stewart GD, Campbell PJ, Wedge DC, Martincorena I, Rampling D, Hook L, Warren AY, Coleman N, Chowdhury T, Sebire N, Drost J, Saeb-Parsy K, Stratton MR, Straathof K, Pritchard-Jones K, Behjati S. Embryonal precursors of Wilms tumor. Science. 2019 Dec 6;366(6470):1247-1251.
HEALTH Investigators, Bhandari M, Einhorn TA, Guyatt G, Schemitsch EH, Zura RD, Sprague S, Frihagen F, Guerra-Farfán E, Kleinlugtenbelt YV, Poolman RW, Rangan A, Bzovsky S, Heels-Ansdell D, Thabane L, Walter SD, Devereaux PJ. Includes McDonnell SM, Khan WS as collaborators. Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture. N Engl J Med. 2019 Dec 5;381(23):2199-2208.
Machado HE, Øbro NF, Mitchell E, Davies M, Green AR, Saeb-Parsy K, Hodson DJ, Kent D, Campbell PJ. Life History of Normal Human Lymphocytes Revealed By Somatic Mutations. Blood. 2019; 134 (Supplement_1): 1045.
Katarivas Levy G, Ong J, Birch M, Justin AW, Markaki A. Albumin-Enriched Fibrin Hydrogel Embedded in Active Ferromagnetic Networks Improves Osteoblast Differentiation and Vascular Self-Organisation. Polymers. 2019;11(11), 1743-1743.
Lee-Six H, Olafsson S, Ellis P, Osborne RJ, Sanders MA, Moore L, Georgakopoulos N, Torrente F, Noorani A, Goddard M, Robinson P, Coorens THH, O’Neill L, Alder C, Wang J, Fitzgerald RC, Zilbauer M, Coleman N, Saeb-Parsy K, Martincorena I, Campbell PJ, Stratton MR. The landscape of somatic mutation in normal colorectal epithelial cells. Nature. 2019 Oct 23; 574:532–537
Chisari E, Yaghmour KM, Khan WS. The effects of TNF-alpha inhibition on cartilage: a systematic review of preclinical studies. Osteoarthritis Cartilage. 2019 Oct 18. pii: S1063-4584(19)31229-4. [Epub ahead of print] Review.
Cumpstey AF, Hennis PJ, Gilbert-Kawai ET, Fernandez BO, Grant D, Jenner W, Poudevigne M, Moyses H, Levett DZ, Cobb A, Meale P, Mitchell K, Pöhnl H, Mythen MG, Grocott MP, Martin DS, Feelisch M, Adams T et al; Xtreme Alps research group. Effects of dietary nitrate supplementation on microvascular physiology at 4559 m altitude – A randomised controlled trial (Xtreme Alps). Nitric Oxide. 2019 Oct 8;94:27-35. [Epub ahead of print]
Klatte T, Gallagher KM, Afferi L, Volpe A, Kroeger N, Ribback S, McNeill A, Riddick ACP, Armitage JN, ‘Aho TF, Eisen T, Fife K, Bex A, Pantuck AJ, Stewart GD. The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort. BMC Med. 2019 Oct 3;17(1):182.
Tanase CE, Qutachi O, White LJ, Shakesheff KM, McCaskie AW, Best SM, Cameron RE. Targeted protein delivery: carbodiimide crosslinking influences protein release from microparticles incorporated within collagen scaffolds. Regen Biomater. 2019 Oct;6(5):279-287.
Martin JL, Costa ASH, Gruszczyk AV, Beach TE, Allen FM, Prag HA, Hinchy EC, Mahbubani K, Hamed M, Tronci L, Nikitopoulou E, James AM, Krieg T, Robinson AJ, Huang MH, Caldwell ST, Logan A, Pala L, Hartley RC, Frezza C, Saeb-Parsy K, Murphy MP. Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation. Nature Metabolism 2019 Sept 30;1(9)
Devoy B, Yaghmour KM, Chisari E, McDonnell SM, Khan W. Perioperative management of renal transplant patients undergoing total joint arthroplasty. J Perioper Pract. 2019 Sep;29(9):270-275.
Kalapara AA, Verbeek JFM, Nieboer D, Fahey M, Gnanapragasam V, Van Hemelrijck M, Lee LS, Bangma CH, Steyerberg EW, Harkin T, Helleman J, Roobol MJ, Frydenberg M. Adherence to Active Surveillance Protocols for Low-risk Prostate Cancer: Results of the Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance Initiative. Eur Urol Oncol. 2019 Sep 26.pii: S2588-9311(19)30140-3.
To K, Crowley C, Lim SK, Khan WS. Autologous adipose tissue grafting for the management of the painful scar. Cytotherapy. 2019 Nov;21(11):1151-1160. Epub 2019 Sep 17. Review.
Katarivas Levy G, Birch MA, Brooks RA, Neelakantan S, Markaki AE. Stimulation of Human Osteoblast Differentiation in Magneto-Mechanically Actuated Ferromagnetic Fiber Networks. J Clin Med. 2019 Sep 22;8(10). pii: E1522.
Lok LSC1,2, Dennison TW1, Mahbubani KM3, Saeb-Parsy K3,4, Chilvers ER5,6, Clatworthy MR. Phenotypically distinct neutrophils patrol uninfected human and mouse lymph nodes. Proc Natl Acad Sci USA. 2019 Sep 4. pii: 201905054. [Epub ahead of print]
Wu DA, Robb ML, Forsythe JLR, Bradley C, Cairns J, Draper H, Dudley C, Johnson RJ, Metcalfe W, Ravanan R, Roderick P, Tomson CRV, Watson CJE, Bradley JA, Oniscu GC. Recipient Comorbidity and Survival Outcomes after Kidney Transplantation: a UK-wide Prospective Cohort Study. Transplantation. 2019 Aug 19. [Epub ahead of print]
Kramer CSM, Franke-van Dijk MEI, Priddey AJ, Pongrácz T, Gnudi E, Car H, Karahan GE, van Beelen E, Zilvold-van den Oever CCC, Rademaker HJ, de Haan N, Wuhrer M, Kosmoliaptsis V, Parren PWH, Mulder A, Roelen DL, Claas FHJ, Heidt S. Recombinant human monoclonal HLA antibodies of different IgG subclasses recognising the same epitope: Excellent tools to study differential effects of donor-specific antibodies. HLA. 2019 Aug 12. doi: 10.1111/tan.13664. [Epub ahead of print]
Summers DM, Ahmad N, Randle LV, O’Sullivan AM, Johnson RJ, Collett DP, Attia M, Clancy M, Tavakoli A, Akyol M, Jamieson NV, Bradley JA, Watson CJE. Transplantation. 2019, Aug 8; [Online]
Li B, Cairns JA, Johnson RJ, Watson CJE, Roderick P, Oniscu GC, Metcalfe W, Bradley JA, Tomson CR, Draper H, Forsythe JL, Dudley C, Ravanan R. Equity-efficiency trade-offs associated with alternative approaches to deceased donor kidney allocation: a patient-level simulation. Transplantation. 2019, Aug 8; [Online]
Berdichevskia A, Birch MA, Markaki AE. Collagen scaffolds with tailored pore geometry for building three-dimensional vascular networks. Materials Letters. 2019 Aug 1; Vol. 248: 93-96
Richards J, Hossain M, Summers D, Slater M, Bartlett M, Kosmoliaptsis V, Wilson EC, Lagaac R, Sidders A, Foley C, Laing E, Hopkins V, Fitzpatrick-Creamer C, Hudson C, Thomas H, Turner S, Tambyraja A, Somalanka S, Hunter J, Dutta S, Lawman S, Salter T, Aslam M, Bagul A, Sivaprakasam R, Smith G, Moinuddin Z, Knight S, Gibbs P, Motallebzadeh R, Barnett N, Pettigrew G; SONAR trial group. Surveillance arterioveNous fistulAs using ultRasound (SONAR) trial in haemodialysis patients: a study protocol for a multicentre observational study. BMJ Open. 2019 Jul 23;9(7):e031210.
Georgiades F, Kosmoliaptsis V, Nicholson ML, Russell NK. Preventing conversion to open surgery during laparoscopic donor nephrectomy complicated by bleeding from the aorta. Clin Transplant. 2019 Jul 22:e13653 [Epub ahead of print]
Barrett T, Slough R, Sushentsev N, Shaida N, Koo BC, Caglic I, Kozlov V, Warren AY, Thankappannair V, Pinnock C, Shah N, Saeb-Parsy K, Gnanapragasam VJ, Sala E, Kastner C. Three-year experience of a dedicated prostate mpMRI pre-biopsy programme and effect on timed cancer diagnostic pathways. Clin Radiol. 2019 Jul 6. pii: S0009-9260(19)30279-X. [Epub ahead of print]
Johnson-Lynn SE, McCaskie AW, Coll AP, Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone Joint Res. 2018 Jun 5;7(5):373-378. eCollection 2018 May.
Richards J, Hossain M, Summers D, Slater M, Bartlett M, Kosmoliaptsis V, Wilson ECF, Lagaac R, Sidders A, Foley C, Laing E, Hopkins V, Fitzpatrick-Creamer C, Hudson C, Thomas H, Turner S, Tambyraja A, Somalanka S, Hunter J, Dutta S, Lawman S, Salter T, 10, Aslam M, Bagul A, Sivaprakasam R, Smith G, Moinuddin Z, Knight S, Gibbs P, Motallebzadeh R, Barnett N, Pettigrew. On behalf of the SONAR trial group. Surveillance Of arterioveNous fistulAe using ultRasound (SONAR) trial in haemodialysis patients: a study protocol for the multicentre observational study. BMJ Open 2019 Jul;0:e031210.
Vieira Braga FA, Kar G, Berg M, Carpaij OA, Polanski K, Simon LM, Brouwer S, Gomes T, Hesse L, Jiang J, Fasouli ES, Efremova M, Vento-Tormo R, Talavera-López C, Jonker MR, Affleck K, Palit S, Strzelecka PM, Firth HV, Mahbubani KT, Cvejic A, Meyer KB, Saeb-Parsy K, Luinge M, Brandsma CA, Timens W, Angelidis I, Strunz M, Koppelman GH, van Oosterhout AJ, Schiller HB, Theis FJ, van den Berge M, Nawijn MC, Teichmann SA. A cellular census of human lungs identifies novel cell states in health and in asthma. Nat Med. 2019 Jun 17.[Epub ahead of print]
Ceresa CDL, Nasralla D, Watson CJE, Butler AJ, Coussios CC, Crick K, Hodson L, Imber C, Jassem W, Knight SR, Mergental H, Ploeg RJ, Pollok JM, Quaglia A, Shapiro AMJ, Weissenbacher A, Friend PJ. Transient cold storage prior to normothermic liver perfusion may facilitate adoption of a novel technology. Liver Transpl. Jun 17.[Epub ahead of print]
Hsu RCJ, Barclay M, Loughran MA, Lyratzopoulos G, Gnanapragasam VJ, Armitage JN. Impact of Hospital Nephrectomy Volume on Intermediate to Long-term Survival in Renal Cell Carcinoma. BJU Int. Jun 17.[Epub ahead of print]
Tysoe OC, Justin AW, Brevini T, Chen SE, Mahbubani KT, Frank AK, Zedira H, Melum E, Saeb-Parsy K, Markaki AE, Vallier L, Sampaziotis F. Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue. Nat Protoc. 2019 Jun;14(6):1884-1925.
Johnson-Lynn SE, McCaskie AW, Coll AP, Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone Joint Res. 2018 Jun 5;7(5):373-378. eCollection 2018 May.
Rossi SH, Blick C, Nathan P, Nicol D, Stewart GD, Wilson ECF. Expert Elicitation to Inform a Cost-Effectiveness Analysis of Screening for Renal Cancer. Value in Health. 2019 May 31 [Epub ahead of print]
Hui Jin Ng N, Binte Jasmen J, Siang Lim C, Hui Lau H, Gomathi Krishnan V, Kadiwala J, Kulkarn RN, Ræder H, Vallier L, Hoon S, Kee Keong Teo A. HNF4A haploinsufficiency in MODY1 abrogates liver and pancreas differentiation from patient-derived iPSCs. iScience. 2019 May 27; epub
Gnanapragasam VJ, Barrett T, Thankapannair V, Thurtle D, Rubio-Briones J, Domínguez-Escrig J, Bratt O, Statin P, Muir K, Lophatananon A. Using prognosis to guide inclusion criteria, define standardized end‐points and stratify follow up in active surveillance for prostate cancer. BJU Int. 2019 May 7 [Epub ahead of print]
Hourston GJ, Barrett MP, Khan WS, Vindlacheruvu M, McDonnell SM. New drug, new problem: do hip fracture patients taking NOACs experience delayed surgery, longer hospital stay, or poorer outcomes? Hip Int. 2019 Apr 25:1120700019841351.[Epub ahead of print]
Gnanapragasam VJ, Barrett T, Massie C, Pacey S, Warren A. Using prognosis to guide early detection and treatment selection in non-metastatic prostate cancer. BJU Int. 2019 Apr;123(4):562-563.
Teresa Brevini, Walid Al-Akkad, Alessandro F Pellegata, Olivia C Tysoe, Luca Frenguelli, Si Emma Chen, Paolo De Coppi, Massimo Pinzani, Kourosh Saeb-Parsy, Ludovic Vallier, Giuseppe Mazza, Fotios Sampaziotis. PS-166-Repopulation of decellularized porcine bile ducts with human cholangiocyte organoids for the generation of human-sized bioengineered biliary tissue. Journal of Hepatology April 2019 Volume 70, Issue 1, Supplement, Pages e103–e104.
Taylor DM, Bradley JA, Bradley C, Draper H, Dudley C, Fogarty D, Fraser S, Johnson R, Leydon GM, Metcalfe W, Oniscu GC, Robb M, Tomson C, Watson CJE, Ravanan R, Roderick P; ATTOM investigators. Limited health literacy is associated with reduced access to kidney transplantation.Kidney Int. 2019 Mar 27. pii: S0085-2538(19)30049-3 [Epub ahead of print]
Klatte T, Stewart GD. Disagreement in risk groups for metastatic renal cancer. Nat Rev Urol. 2019 Mar 25. doi: 10.1038/s41585-019-0174-6. [Epub ahead of print]
Dabestani S, Beisland C, Stewart GD, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandéz-Pello S, Monagas S, Williams SP, Powles T, Van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Increased use of cross-sectional imaging for follow-up does not improve post-recurrence survival of surgically treated initially localized R.C.C.: results from a European multicenter database (R.E.C.U.R.). Scand J Urol. 2019 Mar 25:1-7.
Rossi SH, Fielding A, Blick C, Handforth C, Brown JE, Stewart GD. Setting Research Priorities in Partnership with Patients to Provide Patient-centred Urological Cancer Care. Eur Urol. 2019 Mar 22. pii: S0302-2838(19)30194-0. [Epub ahead of print]
Devoy B, Yaghmour KM, Chisari E, McDonnell SM, Khan W. Perioperative management of renal transplant patients undergoing total joint arthroplasty. J Perioper Pract. 2019, Mar 19:1750458919835435
Thurtle DR, Greenberg DC, Lee LS, Huang HH, Pharoah PD, Gnanapragasam VJ. Individual prognosis at diagnosis in nonmetastatic prostate cancer: Development and external validation of the PREDICT Prostate multivariable model. PLoS Med 2019 Mar 12;16(3).
Syafruddin SE, Rodrigues P, Vojtasova E, Patel SA, Zaini MN, Burge J, Warren AY, Stewart GD, Eisen T, Bihary D, Samarajiwa SA, Vanharanta S. A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma. Nat Commun. 2019 Mar 11;10(1):1152.
Qureshi MS, Alsughayyir J, Chhabra M, Ali JM, Goddard MJ, Devine CA, Conlon TM, Linterman MA, Motallebzadeh R, Pettigrew GJ. Germinal center humoral autoimmunity independently mediates progression of allograft vasculopathy. J Autoimmun. 2019 Mar;98:44-58
Van Hemelrijck M, Ji X, Helleman J, Roobol MJ, van der Linden W, Nieboer D, Bangma CH, Frydenberg M, Rannikko A, Lee LS, Gnanapragasam VJ, Kattan MW; Members of the Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance GAP3 consortium; Members of the Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance GAP3 consortium. Reasons for Discontinuing Active Surveillance: Assessment of 21 Centres in 12 Countries in the Movember GAP3 Consortium. Eur Urol. 2019 Mar;75(3):523-531.
Castro-Dopico T, Dennison TW, Ferdinand JR, Mathews RJ, Fleming A, Clift D, Stewart BJ, Jing C, Strongili K, Labzin LI, Monk EJM, Saeb-Parsy K, Bryant CE, Clare S, Parkes M, Clatworthy MR. Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis. Immunity. 2019 Feb 27. [Epub ahead of print]
Rossi SH, Blick C, Handforth C, Brown JE, Stewart GD; Renal Cancer Gap Analysis Collaborative. Essential Research Priorities in Renal Cancer: A Modified Delphi Consensus Statement. Eur Urol Focus. 2019 Feb 13. [Epub ahead of print]
Merriel SWD, Hetherington L, Seggie A, Castle JT, Cross W, Roobol MJ, Gnanapragasam V, Moore CM. Best practice in Active Surveillance for men with prostate cancer: A Prostate Cancer UK consensus statement. Prostate Cancer UK Expert Reference Group on Active Surveillance. BJU Int. 2019 Feb 11 [Epub ahead of print]
Palmer AJR, Ayyar Gupta V, Fernquest S, Rombach I, Dutton SJ, Mansour R, Wood S, Khanduja V, Pollard TCB, McCaskie AW, Barker KL, Andrade TJMD, Carr AJ, Beard DJ, Glyn-Jones S; FAIT Study Group. Arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of symptomatic femoroacetabular impingement: multicentre randomised controlled trial. BMJ. 2019, Feb 7;364:l185.
Ranmuthu CDS, Ranmuthu CKI, Russell JC, Singhania D, Khan WS. Are the Biological and Biomechanical Properties of Meniscal Scaffolds Reflected in Clinical Practice? A Systematic Review of the Literature. Int J Mol Sci. 2019, Feb 1;20(3).
Smith SF, Miakhil SI, Lockett C. An unusual cause of testicular pain: single organ lymphocytic vasculitis. Journal of Clinical Urology. 2019, Feb. Epub.
Yaghmour KM, Chisari E, Khan WS. Single-Stage Revision Surgery in Infected Total Knee Arthroplasty: A PRISMA Systematic Review. J Clin Med. 2019, Feb 2;8(2).
Summers DM, Pettigrew GJ. Uncontrolled DCD donation-tilting at windmills or pushing against an open door? Kidney Int. 2019 Feb;95(2):263-265.
Chhabra M, Alsughayyir J, Qureshi MS, Mallik M, Ali JM, Gamper I, Moseley EL, Peacock S, Kosmoliaptsis V, Goddard MJ, Linterman MA, Motallebzadeh R, Pettigrew GJ. Germinal Center Alloantibody Responses Mediate Progression of Chronic Allograft Injury. Front Immunol. 2019 Jan 23;9:3038.
Thompson ER, Irwin EA, Trotter P, Ibrahim IK, Tingle SJ, White SA, Manas DM, Wilson CH. UK registry analysis of donor substance misuse and outcomes following pancreas transplantation. Clin Transplant. 2019 Jan 19:e13481.
Alsughayyir A, Chhabra M, Qureshi MS, Mallik M, Ali JM, Gamper I, Moseley EL, Peacock S, Kosmoliaptsis K, Goddard MJ, Linterman MA, Motallebzadeh R and Pettigrew GJ. Relative Frequencies of Alloantigen-Specific Helper CD4 T Cells and B Cells Determine Mode of Antibody-Mediated Allograft Rejection. Front Immunol. 2019 Jan; 9 article 3039.
Taylor R, Allen E, Richards JA, Goh AM, Neuberger J, Collett D, Pettigrew GJ On behalf of members of the Liver Advisory Group to NHS Blood Transplant. Survival advantage for patients accepting the offer of a circulatory death liver transplant. Journal of Hepatology. 2019 Jan. Epub
Tsekes D, Konstantopoulos G, Khan WS, Rossouw D, Elvey M, Singh J. Use of stem cells and growth factors in rotator cuff tendon repair. Eur J Orthop Surg Traumatol. 2019 Jan 9. [Epub ahead of print]
Smith SF, Hosgood SA, Nicholson ML. Ischemia-reperfusion injury in renal transplantation: 3 key signaling pathways in tubular epithelial cells. Kidney Int. 2019 Jan;95(1):50-56. Review.
2018
Qureshi MS, Alsughayyir J, Chhabra M, Ali JM, Goddard MJ, Devine C, Conlon TM, Linterman MA, Motallebzadeh R, Pettigrew GJ. Data regarding transplant induced germinal center humoral autoimmunity. Data Brief. 2018 Dec 28;22:647-657
Watson CJE, Hunt F, Messer S, Currie I, Large S, Sutherland A, Crick K, Wigmore SJ, Fear C, Cornateanu S, Randle LV, Terrace JD, Upponi S, Taylor R, Allen E, Butler AJ, Oniscu GC. In situ normothermic perfusion of livers in controlled circulatory death donation may prevent ischemic cholangiopathy and improve graft survival. Am J Transplant. 2018 Dec 27. [Epub ahead of print]
Tanase CE, Golozar M, Best SM, Brooks RA. Cell response to plasma electrolytic oxidation surface-modified low-modulus β-type titanium alloys. Colloids Surf B Biointerfaces. 2018 Dec 26;176:176-184. [Epub ahead of print]
Dolezalova N, Gruszczyk A, Mahbubani KTA, Casey J, Slater NKH, Saeb-Parsy K. Characterising diffusion kinetics to improve pancreatic islet cryopreservation. Cryobiology. Volume 85, December 2018, Pages 144-145
Gnanapragasam V, Barrett T, Massie C, Pacey S, Warren A. Using prognosis to guide early detection and treatment selection in non-metastatic prostate cancer. BJU International. 2018 Nov 30. [Epub ahead of print]
Stacey G, Andrews P, Asante C, Barbaric I, Barry J, Bisset L, Braybrook J, Buckle R, Chandra A, Coffey P, Crouch S, Driver P, Evans A, Gardner J, Ginty P, Goldring C, Hay DC, Healy L, Hows A, Hutchinson C, Jesson H, Kalber T, Kimber S, Leathers R, Moyle S, Murray T, Neale M, Pan D, Park BK, Rebolledo RE, Rees I, Rivolta MN, Ritchie A, Roos EJ, Saeb-Parsy K, Schröder B, Sebastien S, Thomas A, Thomas RJ, Turner M, Vallier L, Vitillo L, Webster A, Williams D. Science-based assessment of source materials for cell-based medicines: report of a stakeholders workshop. Regen Med. 2018 Nov 29. [Epub ahead of print]
Mylonas KJ, Anderson J, Sheldrake TA, Hesketh EE, Richards JA, Ferenbach DA, Kluth DC, Savill J, Hughes J. Granulocyte macrophage-colony stimulating factor: A key modulator of renal mononuclear phagocyte plasticity. Immunology. 2018 Nov 9 Epub
Siu JHY, Surendrakumar V, Richards JA, Pettigrew GJ. T cell Allorecognition Pathways in Solid Organ Transplantation. Frontiers in Immunology. 2018 Nov Epub.
Martincorena I, Fowler JC, Wabik A, Lawson ARJ, Abascal F, Hall MWJ, Cagan A, Murai K, Mahbubani K, Stratton MR, Fitzgerald RC, Handford PA, Campbell PJ, Saeb-Parsy K, Jones PH. Somatic mutant clones colonize the human esophagus with age. Science. 2018 Nov 23;362(6417):911-917. Epub 2018 Oct 18.
Beisland C, Dabestani S, Stewart G, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandéz-Pello S, Monagas S, Williams SP, Torbrand C, Powles T, Van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Making a judgement on the potential curability of recurrent Renal Cell Carcinoma (RCC): Differences in global per protocol vs. investigator based assessment. European Urology Supplements. 2018 Nov 17(14) e3025–e3026.
Mallon DH, Kling C, Robb M, Ellinghaus E, Bradley JA, Taylor CJ, Kabelitz D, Kosmoliaptsis V. Predicting Humoral Alloimmunity from Differences in Donor and Recipient HLA Surface Electrostatic Potential. Journal of Immunology. 2018 Nov 14 pii: ji1800683. [Epub ahead of print]
Mouliere F, Chandrananda D, Piskorz AM, Moore EK, Morris J, Ahlborn LB, Mair R, Goranova T, Marass F, Heider K, Wan JCM1, Supernat A, Hudecova I, Gounaris I, Ros S, Jimenez-Linan M, Garcia-Corbacho J, Patel K, Østrup O, Murphy S, Eldridge MD, Gale D, Stewart GD, Burge J, Cooper WN, van der Heijden MS, Massie CE, Watts C, Corrie P, Pacey S, Brindle KM, Baird RD, Mau-Sørensen M, Parkinson CA, Smith CG, Brenton JD, Rosenfeld N. Enhanced detection of circulating tumor DNA by fragment size analysis. Science Translational Medicine. 2018 Nov 7;10(466). pii: eaat4921.
Serrano F, Bernard WG, Granata A, Iyer D, Steventon B, Kim M, Vallier L, Gambardella L, Sinha S. A novel human pluripotent stem cell-derived neural crest model of Treacher Collins Syndrome shows defects in cell death and migration. Stem Cells and Development. 2018 Oct 30. [Epub ahead of print]
Grandy R, Tomaz R, Vallier L. Modeling Disease with Inducible Pluripotent Stem Cells. Annual Review of Pathology. 2018 Oct 24. [Epub ahead of print]
Nicholson ML, Yong C, Trotter PB, Grant L, Hosgood SA. Risk factors for transplant renal artery stenosis after live donor transplantation. British Journal of Surgery. 2018 Oct 22. [Epub ahead of print]
DiRito JR, Hosgood SA, Tietjen GT, Nicholson ML. The future of marginal kidney repair in the context of normothermic machine perfusion. Am J Transplant. 2018 Oct;18(10):2400-2408
Rashidi H, Luu NT, Alwahsh SM, Ginai M, Alhaque S, Dong H, Tomaz RA, Vernay B, Vigneswara V, Hallett JM, Chandrashekran A, Dhawan A, Vallier L, Bradley M, Callanan A, Forbes SJ, Newsome PN, Hay DC. 3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo. Archives of Toxicology. 2018 Oct;92(10):3117-3129.
Van Hemelrijck M, Ji X2, Helleman J, Roobol MJ, van der Linden W, Nieboer D, Bangma CH, Frydenberg M, Rannikko A, Lee LS, Gnanapragasam VJ, Kattan MW. Reasons for Discontinuing Active Surveillance: Assessment of 21 Centres in 12 Countries in the Movember GAP3 Consortium. European Urology. 2018 Oct 29. pii: S0302-2838(18)30813-3. [Epub ahead of print]
Hsu RCJ, Barclay M, Loughran MA, Lyratzopoulos G, Gnanapragasam VJ, Armitage JN. Time trends in service provision and survival outcomes for patients with renal cancer treated by nephrectomy in England 2000-2010. BJU International. 2018 Oct;122(4):599-609.
Dabestani S, Beisland C, Stewart GD, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandéz-Pello S, Monagas S, Williams SP, Torbrand C, Powles T, Van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Intensive Imaging-based Follow-up of Surgically Treated Localised Renal Cell Carcinoma Does Not Improve Post-recurrence Survival: Results from a European Multicentre Database (RECUR). European Urology. 2018 Oct 11. pii: S0302-2838(18)30748-6.[Epub ahead of print]
Lloyd T, Patruno G, Macchi A, Czarniecki M, Gnanapragasam V, Koo B, Saeb-Parsy K, Nadeem S, Warren A, Bratt O, Shah N, Barrett T, Kastner C. “Saturation target biopsies” – can a reduction in biopsy cores maintain accuracy of mpMRI supported target and systematic trans-perineal prostate biopsies? European Urology Supplements. 2018 Sept, Vol. 17, Issue 8, p313
Mongelli L, Patruno G, Blumenthal Y, Warren A, Koo B, Gnanapragasam V, Saeb-Parsy K, Barrett T, Kastner C. The impact of prostate MRI-based transperineal biopsies (M-TPBx) on an Active Surveillance (ActS) practice in a tertiary referral centre. European Urology Supplements. 2018 Sept, Vol. 17, Issue 8, p220
Usman A, Yuan J, Patterson AJ, Graves MJ, Varty K, Sadat U, Gillard JH, Neovascularization in Vertebral Artery Atheroma-A Dynamic Contrast-Enhanced Magnetic Resonance Imaging-Based Comparative Study in Patients with Symptomatic and Asymptomatic Carotid Artery Disease. J Stroke Cerebrovasc Dis. 2018 Sep;27(9):2505-2512
Klatte T, Stewart GD. Renal cell carcinoma: standards and controversies. World Journal Urology. 2018 Sep 12 [Epub ahead of print]
Ranmuthu CDS, Ranmuthu CKI, Khan WS. Evaluating the Current Literature on Treatments Containing Adipose-Derived Stem Cells for Osteoarthritis: a Progress Update. Current Rheumatology Reports. 2018 10;20(11):67 Review
Tarkin JM, Le EPV, Calcagno C, Dweck MR,Evans NR, Chowdhury MM, Newby DE, Fayad ZA, Bennett MR, Rudd JHF. 68Ga-DOTATATE PET identifies myocardial inflammation and bone marrow monocyte mobilisation after myocardial infarction. Cardiovascular Research. 2018 Sep 114(suppl_2):S9-S10
Woods S, Barter MJ, Elliott HR, McGillivray CM, Birch MA, Clark IM, Young DA. miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse. Matrix Biology. 2018 Sep 5. [Epub ahead of print]
Sadat U, Mariam NBG, Usman A, Chowdhury MM, El Nakhai E, DaCosta, OF, Gillard JH, Hayes PD, Varty K. Association Between Abdominal Visceral Artery Calcification and All-Cause Mortality-A Computerized Tomography Imaging-Based Longitudinal Follow-Up Study. Angiology. 2018 Sep 4 [Epub ahead of print]
Tcacencu I, Rodrigues N, Alharbi N, Benning M, Toumpaniari S, Mancuso E, Marshall M, Bretcanu O, Birch MA, McCaskie AW and Dalgarno KW. Osseointegration of porous apatite-wollastonite and poly (lactic acid) composite structures created using 3D printing techniques. Materials Science and Engineering: C. 2018 Aug 90, 1-7
Frith TJ, Granata I, Wind M, Stout E, Thompson O, Neumann K, Stavish D, Heath PR, Ortmann D, Hackland JO, Anastassiadis K, Gouti M, Briscoe J, Wilson V, Johnson SL, Placzek M, Guarracino MR, Andrews PW, Tsakiridis A. Human axial progenitors generate trunk neural crest cells in vitro. eLife. 2018 Aug 10;7. pii: e35786.
Duan P, Toumpaniari R, Partridge S, Birch MA, Genever PA, Bull SJ, Dalgarno KW, McCaskie AW and Chen J. How cell culture conditions affect the microstructure and nanomechanical properties of extracellular matrix formed by immortalized human mesenchymal stem cells: An experimental and modelling study. Materials Science and Engineering: C. 2018 Aug 89, 149-159
Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S. Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors. Science. 2018 Aug 10;361(6402):594-599.
Steinberg J, Brooks RA, Southam L, Bhatnagar S, Roumeliotis TI, Hatzikotoulas K, Zengini E, Wilkinson JM, Choudhary JS, McCaskie AW and Zeggini E. Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology (Oxford) 2018 Aug 1;57(8):1481-1489
Wiebe C, Kosmoliaptsis V, Pochinco D, Taylor C, Nickerson PA. Comparison of HLA Molecular Mismatch Methods to Determine HLA Immunogenicity. Transplantation. Aug;102(8):1338-1343.
Mitchell TJ, Rossi SH, Klatte T, Stewart GD. Genomics and clinical correlates of renal cell carcinoma World Journal of Urology. 2018 Aug 11. [Epub ahead of print]
Marconi L, de Bruijn R, van Werkhoven E, Beisland C, Fife K, Heidenreich A, Kapoor A, Karam J, Kauffmann C, Klatte T, Ljungberg B, Matin S, Sjoberg D, Staehler M, Stewart GD, Tanguay S, Uzzo R, Welsh S, Wood L, Wood C, Bex A. External validation of a predictive model of survival after cytoreductive nephrectomy for metastatic renal cell carcinoma. World Journal of Urology. 2018 Aug 1 [Epub ahead of print]
Copley HC, Elango M, Kosmoliaptsis V. Assessment of human leukocyte antigen immunogenicity: current methods, challenges and opportunities. Current Opinion in Organ Transplant. 2018 Aug;23(4):477-485.
Archer DE, Mafi R, Mafi P, Khan W. Preclinical Studies on Biomaterial Scaffold use in Knee Ligament Regeneration: A systematic review. Current Stem Cell Research & Therapy. 2018;13(8):691-701
DiRito JR, Hosgood SA, Tietjen GT, Nicholson ML. The future of marginal kidney repair in the context of normothermic machine perfusion. Am J Transplant. 2018 Oct;18(10):2400-2408. Epub 2018 Jul 2. Review.
Rodrigues P, Patel SA, Harewood L, Olan I, Vojtasova E, Syafruddin SE, Zaini MN, Richardson EK, Burge J, Warren AY, Stewart GD, Saeb-Parsy K, Samarajiwa SA, Vanharanta S. NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis. Cancer Discovery. 2018 Jul;8(7):850-865.
Arshad Z, Pettitt DA, Chadha P, Davies B, Carr A, Walmsley P. Artificial Intelligence to Predict Periprosthetic Joint Infection after Total Hip Replacement. International Journal of Surgery. 2018 July; 55:S8
Thurtle D, Barrett T, Thankappan-Nair V, Koo B, Warren A, Kastner C, Saeb-Parsy K, Kimberley-Duffell J, Gnanapragasam VJ. Progression and treatment rates using an active surveillance protocol incorporating image-guided baseline biopsies and multiparametric magnetic resonance imaging monitoring for men with favourable-risk prostate cancer. BJU International. 2018 Jul;122(1):59-65.
Hurrell T, Segeritz CP, Vallier L, Lilley KS, Cromarty AD. Proteomic Comparison of Various Hepatic Cell Cultures for Preclinical Safety Pharmacology. Toxicological Science. 2018 Jul 1;164(1):229-239.
Banham GD, Flint SM, Torpey N, Lyons PA, Shanahan DN, Gibson A, Watson CJE, O’Sullivan AM, Chadwick JA, Foster KE, Jones RB, Devey LR, Richards A, Erwig LP, Savage CO, Smith KGC, Henderson RB, Clatworthy MR. Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial. Lancet. 2018 Jun 14. pii: S0140-6736(18)30984-X. Epub 2018 Jun 14
Thurtle D, Gordon E, Brierly R, Conway CJ, McLoughlin J. GP perception of prostate-specific antigen testing has improved, but more awareness of prostate cancer risk in younger patients is still awaited. Prostate international. 2018 Jun;6(2):61-65.
Johnson-Lynn SE, McCaskie AW, Coll AP and Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone and Joint Research. 2018 Jun 5;7(5):373-378
Segeritz CP, Rashid ST, Cardoso de Brito M, Paola MS, Ordonez A, Morell CM, Kaserman JE, Madrigal P, Hannan N, Gatto L, Tan L, Wilson AA, Lilley K, Marciniak SJ, Gooptu B, Lomas DA, Vallier L. hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency. Journal of Hepatology. 2018 Jun 4. pii: S0168-8278(18)32113-5.
Martin JL, Gruszczyk AV, Beach TE, Murphy MP, Saeb-Parsy K. Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury. Pediatric Nephrology. 2018 Jun 2. [Epub ahead of print]
Chowdhury MM, Rudd JHF, Coughlin PA. Response to “Re. Abdominal Aortic Aneurysm Calcification: Are Biochemical Markers a Missing Piece of the Puzzle?” European Journal of Vascular and Endovascular Surgery. 2018 Jun;55(6):900-901
Oniscu GC, Watson CJE, Wigmore SJ. Redefining futility in DCD liver transplantation in the era of novel perfusion technologies. Journal of Hepatology. 2018 Jun;68(6):1327-1328.
Kwon K-A, Juhasz JA, Brooks RA. Best SM. Bioactive conformable hydrogel-carbonated hydroxyapatite nanocomposite coatings on Ti-6Al-4V substrates. Materials Technology 2018 June [published online]
Ardakani AHG, Khan WS. The role of ageing and gender in musculoskeletal stem cell. Current Stem Cell Research & Therapy, 2018 13(6):432-437
Thurtle D, Starling L, Leonard K, Stone T, Gnanapragasam VJ. Improving the safety and tolerability of local anaesthetic outpatient transperineal prostate biopsies: A pilot study of the CAMbridge PROstate Biopsy (CAMPROBE) method. Journal of Clinical Urology. 2018 May;11(3):192-199.
Nasralla D, Coussios CC, Mergental H, Akhtar MZ, Butler AJ, Ceresa CDL, Chiocchia V, Dutton SJ, García-Valdecasas JC, Heaton N, Imber C, Jassem W, Jochmans I, Karani J, Knight SR, Kocabayoglu P, Malagò M, Mirza D, Morris PJ, Pallan A, Paul A, Pavel M, Perera MTPR, Pirenne J, Ravikumar R, Russell L, Upponi S, Watson CJE, Weissenbacher A, Ploeg RJ, Friend PJ; Consortium for Organ Preservation in Europe. A randomized trial of normothermic preservation in liver transplantation. Nature. 2018 May;557(7703):50-56.
MacKay JW, Kapoor G, Driban JB, Lo GH, McAlindon TE, Toms AP, McCaskie AW and Gilbert FJ. Association of subchondral bone texture on magnetic resonance imaging with radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative Bone Ancillary Study. European Radiology. 2018 May 2. [Epub ahead of print]
Gill EL, Li X, Birch MA, Huang YYS. Multi-length scale bioprinting towards simulating microenvironmental cues. Biodes Manuf. 2018, May 1(2):77-88. [Epub]
Hodgson B, Mafi R, Mafi P, Khan WS. The Regulation of Differentiation of Mesenchymal Stem-cells into Skeletal Muscle: A Look at Signalling Molecules Involved in Myogenesis. Current stem cell research & therapy 2018 13(5), 384-407
Khan H, Mafi P, Mafi R, Khan W. The effects of ageing on differentiation and characterisation of human mesenchymal stem cells. Current stem cell research & therapy 2018 13(5), 378-383
Zengini E, Hatzikotoulas K, Tachmazidou I, Steinberg J, Hartwig FP, Southam L, Hackinger S, Boer CG, Styrkarsdottir U, Gilly A, Suveges D, Killian B, Ingvarsson T, Jonsson H, Babis GC, McCaskie A, Uitterlinden AG, van Meurs JBJ, Thorsteinsdottir U, Stefansson K, Davey Smith G, Wilkinson JM, Zeggini E. Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. Nature Genetics. 2018 Apr;50(4):549-558.
Baird A, Lindsay T, Everett A, Iyemere V, Paterson YZ, McClellan A, Henson FMD and Guest DJ. Osteoblast differentiation of equine induced pluripotent stem cells. Biology Open: 2018 7(5)bio.033514
Mitchell TJ, Turajlic S, Rowan A, Nicol D, Farmery JHR, O’Brien T, Martincorena I, Tarpey P, Angelopoulos N, Yates LR, Butler AP, Raine K, Stewart GD, Challacombe B, Fernando A, Lopez JI, Hazell S, Chandra A, Chowdhury S, Rudman S, Soultati A, Stamp G, Fotiadis N, Pickering L, Au L, Spain L, Lynch J, Stares M, Teague J, Maura F, Wedge DC, Horswell S, Chambers T, Litchfield K, Xu H, Stewart A, Elaidi R, Oudard S, McGranahan N, Csabai I, Gore M, Futreal PA, Larkin J, Lynch AG, Szallasi Z, Swanton C, Campbell PJ; TRACERx Renal Consortium. Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal. Cell. 2018 Apr 19;173(3):611-623.e17.
Yiangou L, Ross ADB, Goh KJ, Vallier L. Human Pluripotent Stem Cell-Derived Endoderm for Modeling Development and Clinical Applications. Cell Stem Cell. 2018 Apr 5;22(4):485-499.
Xing Y, Zhao S, Wei Q, Gong S, Zhao X, Zhou F, Ai-Lamki R, Ortmann D, Du M, Pedersen R, Shang G, Si S, Morrell NW, Yang J. A novel piperidine identified by stem cell-based screening attenuates pulmonary arterial hypertension by regulating BMP2 and PTGS2 levels. European Respiratory Journal. 2018 Apr 4;51(4). pii: 1702229.
Kohlhauer M, Dawkins S, Costa ASH, Lee R, Young T, Pell VR, Choudhury RP, Banning AP, Kharbanda RK; Oxford Acute Myocardial Infarction (OxAMI) Study, Saeb-Parsy K, Murphy MP, Frezza C, Krieg T, Channon KM. Metabolomic Profiling in Acute ST-Segment-Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia-Reperfusion Injury. Journal of the American Heart Association. 2018 Apr 6;7(8). pii: e007546. doi: 10.1161/JAHA.117.007546.
Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D’Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A. Report of the Key Opinion Leaders Meeting on Stem Cell-Derived Beta Cells.Transplantation. 2018 Apr 30.
Trotter PB, Summers DM, Ushiro-Lumb I, Robb M, Bradley JA, Powell J, Watson CJE, Neuberger J. Use of Organs From Hepatitis C Virus-Positive Donors for Uninfected Recipients: A Potential Cost-Effective Approach to Save Lives? Transplantation. 2018 Apr;102(4):664-672.
Klatte T, Rossi SH, Stewart GD. Prognostic factors and prognostic models for renal cell carcinoma: a literature review. World Journal of Urology. 2018 Apr 30. [Epub ahead of print]
Rossi SH, Klatte T, Usher-Smith J, Stewart GD.(2018) Epidemiology and screening for renal cancer. World J Urol. 2018 Apr 2. [Epub ahead of print]
Hosgood SA, Moore T, Qurashi M, Adams T, Nicholson ML. Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. Artificial Organs. 2018 Apr 2. [Epub ahead of print]
Tonkin-Crine S, Pruthi R, Taylor DM, Leydon GM, Calestani M, Oniscu GC, Bradley JA, Tomson CR, Bradley C, Dudley C, Watson CJE, Draper H, Johnson RJ, Metcalfe W, Fogarty DG, Ravanan R, Roderick P. Assessing Consensus Between UK Renal Clinicians on Listing for Kidney Transplantation: A Modified Delphi Study. Transplant Direct. 2018 Apr 18;4(5):e343.
Khan WS. Outcomes of alveolar soft part sarcoma from a regional tumour unit. Acta Orthopaedica Belgica 2018 April [published online]
Khan S, Mafi P, Mafi R, Khan W. A Systematic Review of Mesenchymal Stem Cells in Spinal Cord Injury, Intervertebral Disc Repair and Spinal Fusion. Current stem cell research & therapy 2018 13(4), 316-323
Killington K, Mafi R, Mafi P, Khan WS. A systematic review of clinical studies investigating mesenchymal stem cells for fracture non-union and bone defects. Current stem cell research & therapy 2018 13(4), 284-291
MacKay JW, Low SBL, Smith TO, Toms AP, McCaskie AW. and Gilbert FJ. Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis. Osteoarthritis & Cartilage. 2018 Mar 14. pii: S1063-4584(18)31069-0.
Hosgood SA, Thompson E, Moore T, Wilson CH, Nicholson ML. Normothermic machine perfusion for the assessment and transplantation of declined human kidneys from donation after circulatory death donors. British Journal of Surgery. 2018 Mar;105(4):388-394.
Borakati A, Mafi R, Mafi P, Khan WS. A systematic review and meta-analysis of clinical trials of mesenchymal stem cell therapy for cartilage repair. Current stem cell research & therapy 2018 13(3), 215-225
Bertero A, Brown S, Madrigal P, Osnato A, Ortmann D, Yiangou L, Kadiwala J, Hubner NC, de Los Mozos IR, Sadée C, Lenaerts AS, Nakanoh S, Grandy R, Farnell E, Ule J, Stunnenberg HG, Mendjan S, Vallier L. The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency. Nature. 2018 Mar 8;555(7695):256-259.
Dabestani S, Beisland C, Stewart GD, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandéz-Pello S, Monagas S, Williams SP, Torbrand C, Powles T, Van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Long-term Outcomes of Follow-up for Initially Localised Clear Cell Renal Cell Carcinoma: RECUR Database Analysis. European Urolology Focus. 2018 Mar 7. [Epub ahead of print]
Watson CJE, Jochmans I. From “Gut Feeling” to Objectivity: Machine Preservation of the Liver as a Tool to Assess Organ Viability. Current Transplantation Reports. 2018 March;5(1):72-81.
O’Keeffe LM, Ramond A, Oliver-Williams C, Willeit P, Paige E, Trotter P, Evans J, Wadström J, Nicholson M, Collett D, Di Angelantonio E. Mid- and Long-Term Health Risks in Living Kidney Donors: A Systematic Review and Meta-analysis. Annals of Internal Medicine. 2018 Feb 20;168(4):276-284.
Watson CJE, Kosmoliaptsis V, Pley C, Randle L, Fear C, Crick K, Gimson AE, Allison M, Upponi S, Brais R, Jochmans I, Butler AJ. Observations on the ex situ perfusion of livers for transplantation. American Journal of Transplantation. 2018 Feb 8. [Epub ahead of print]
Lydon H, Brooks R, McCaskie A, Henson F. Peripheral mononuclear blood cell apheresis in a preclinical ovine model. BMC Veterinary Research. 2018 Feb 13;14(1):47.
Lawton JM, Habib M, Ma B, Brooks RA, Best SM, Lewis AL, Rushton N, Bonfield W. Correction to: The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo. Journal of Materials Science: Materials in Medicine. 2018 Feb 22;29(3):26
Bertero A, Yiangou L, Brown S, Ortmann D, Pawlowski M, Vallier L. Conditional Manipulation of Gene Function in Human Cells with Optimized Inducible shRNA. Current Protocols in Stem Cell Biology. 2018 Feb 28;44:5C.4.1-5C.4.48.
Briggs W, Guevel B, McCaskie AW and McDonnell SM. Multi- and univariate analyses of the weekend effect for elective lower-limb joint replacements. Annals of the Royal College of Surgeons England. 2018 Jan;100(1):42-46.
Hakeem A, Chen J, Iype S, Clatworthy M, Watson C, Godfrey EM, Upponi S, Saeb-Parsy K. Pancreatic Allograft Thrombosis: Suggestion for a CT grading system and management algorithm. American Journal of Transplantation 2018 18(1):163-179.
Books and Chapters
Williams N, O’Connell PR and McCaskie AW (Editors) (2018). Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
McCaskie AW and Bradley A (2018) Tissue Engineering and Regeneration Part 1: Basic Principles, ch.4, pp.33-41. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC PressWilliams N, O’Connell PR and McCaskie AW (Editors) (2018).
McDonnell SM and Pandit HG (2018) History taking and clinical examination in musculoskeletal disease. Part 5: Elective Orthopaedics, ch.31 pp.436-462. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Khanduja V and Khan W (2018) Hip and Knee Part 5: Elective Orthopaedics, ch.35 pp.511-523. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Seah MKT, Khan W (2018) Minimally Invasive Surgery of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.5 pp.73-85
Seah MKT, Khan W (2018) Computer-Assisted Navigation of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.6 pp.87-99
2017
2016
