2022
James AM, Burger N, Saeb-Parsy K, Casey AM, et al. Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury. Science Direct, Redox Biology. 2022 August.
Gnanapragasam V, Bratt O, Stenman C, Abrahamsson E, Redsäter M. Rates of Positive Abdominal Computed Tomography and Bone Scan Findings Among Men with Cambridge Prognostic Group 4 or 5 prostate cancer: A Nationwide Registry Study. Science Direct, European Urology Open Science. 2022 July.
Stewart GD, Welsh S, Mitchell T, Bex A, Eisen T, et al. A Phase II study of neoadjuvant axitinib for reducing the extent of venous tumour thrombus in clear cell renal cell cancer with venous invasion (NAXIVA). British Journal of Cancer. June 2022 23.
Saeb-Parsy K, Mahbubani K, Moore L, Stratton MR, et al. Abstract 226: Recurrent trisomies, variable selection and precancerous evolution in the normal gastric epithelium. Cancer Research. 2022 June 15.
Stewart GD, Samarajiwa S, Carroll JS, Warren AY, Patel S, et al. The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer. Nature. 2022 June 8.
Saeb-Parsy K, Jones JL, Mahbubani K, Rainbow DB, Polanski K, et al. Cross-tissue immune cell analysis reveals tissue-specific features in humans. Science. 2022 May 13. Vol 376, Issue 6594.
Vallier L, French PJ, Simons, BD, Verstegen M, et al. Human branching cholangiocyte organoids recapitulate functional bile duct formation. Cell Stem Cell. 2022 May 5.
Stewart GD, Harrison H, Li N, Dennis J, Usher-Smith JA, et al. The current state of genetic risk models for the development of kidney cancer: a review and validation. BJU International. 2022 April 22.
Watson C, Berman M, Jothidasan A, Mehta V, Venkateswaran R, et al. UK National DCD Heart Transplant Program – First Year Experience. The Journal of Heart and Lung Transplantation. 2022 April 7.
Khan WS, Lee E, Lu V, Epanomeritakis I. The Use of Autologous Chondrocyte and Mesenchymal Stem Cell Implants for the Treatment of Focal Chondral Defects in Human Knee Joints—A Systematic Review and Meta-Analysis. International Journal of Molecular Sciences. 2022 April 6.
Kosmoliaptsis V, Meisl G, Morgunov A, Aguzzi A, Knowles T, et al. Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2. ACS Infectious Diseases. 2022 March 30.
Stewart GD, Eisen T, Frangou E, Davis ID, et al. External Validation of the 2003 Leibovich Prognostic Score in Patients Randomly Assigned to SORCE, an International Phase III Trial of Adjuvant Sorafenib in Renal Cell Cancer. Journal of Clinical Oncology. 2022 February 25.
Davies BM, Carter AR, Brindley DA. A scoping review of the treatment of hypertrophic scars and keloids. Dermatological Reviews. 2022 February 21.
Henson FMD, McCaskie AW, Jones M, Marris C, Pernstich C, Whitty C. Sustained delivery of the bone morphogenetic proteins BMP-2 and BMP-7 for cartilage repair and regeneration in osteoarthritis. Osteoarthritis and Cartilage Open. 2022 March. Vol 4, Issue 1 100240.
Gnanapragasam V, Barrett T, Pacey S, Leonard K, Wulff J, Funingana I. A Feasibility Study of the Therapeutic Response and Durability of Short-term Androgen-targeted Therapy in Early Prostate Cancer Managed with Surveillance: The Therapeutics in Active Prostate Surveillance (TAPS01) Study. European Urology Open Science. 2022 February.
Watson C, Callaghan CJ, Tomlinson LA, Ibrahim M, Brunskill S, et al. Donor-Transmitted Cancer in Orthotopic Solid Organ Transplant Recipients: A Systematic Review. Transplant International. 2022 February 4.
Stewart GD, Mitchell T, Eisen T, Graves MJ, Barrett T, Welsh S, et al. Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma—A Proof of Principle Study. Cancers. 2022 January 11.
Gnanapragasam V, Russell B, Aning J, Liyanage SH, Page T, et al. MRI-based nomogram for the prediction of prostate cancer diagnosis: A multi-centre validated patient–physician decision tool. Journal of Clinical Urology. 2022 January 7.
2021
Davies BM, Rawal J, Hull P, Carrothers AD, et al. Major trauma care at a regional trauma centre during the COVID-19 lockdown in England. Annals of The Royal College of Surgeons of England. 2021 December.
Gnanapragasam V, Barrett T, Berry B, Richoz N, et al. Resolving the immune landscape of human prostate at a single-cell level in health and cancer. Cell Reports. 2021 December 21. Volume 37, Issue 12.
Hosgood S, Nicholson ML, Ferdinand J, Bates L, et al. MicroRNA antagonist therapy during normothermic machine perfusion of donor kidneys. American Journal of Transplantation. 2021 December 21.
Elliott TR, Hosgood S, Nicholson ML, Kosmoliaptsis V, Ashcroft J, Leighton P. Extracellular Vesicles in Kidney Transplantation: A State of the Art Review. Kidney International. 2021 November 26.
Vallier L, Tyser RCV, Mahammadov E, Nakanoh S, Scialdone A, Srinivas S. Single-cell transcriptomic characterization of a gastrulating human embryo. Nature. 2021 November 17.
Stewart GD, Grayling MJ, Mossop H, Gallagher FA, Welsh SJ, Wason JMS. Advantages of multi-arm non-randomised sequentially allocated cohort designs for Phase II oncology trials. British Journal of Cancer. 2021 November 08.
Stewart GD, Zhou Y, Walter F, Abel G, Hamilton W, et al. Identifying opportunities for timely diagnosis through patterns of primary care tests in patients with bladder and renal cancer: a longitudinal linked data study. British Journal of General Practice. 2021 October 20.
Davies BM, Hull P, Ghobrial M, Hussain A, Carrothers AD, Rawal J, Chou D. 1085 Equestrian Related Pelvic and Acetabular Fractures – Experience from a Major Trauma Centre in England. British Journal of Surgery. 2021 October 12. Volume 108, Issue Supplement_6.
Chowdhury MM, Le E, Rudd JH, Tarkin J, Evans N. 875 Using Stress Testing to Identify Vulnerabilities in Artificial Intelligence Models for the Identification of Culprit Carotid Lesions in Cerebrovascular Events. British Journal of Surgery. 2021 October 12. Volume 108, Issue Supplement_6.
Stewart GD, Dabestani S, Fossati N, Järvinen P, et al. Impact of surgical approach (open vs. minimally invasive) on oncological outcomes after nephrectomy for localised renal cell carcinoma: a recur database project. European Urology Open Science. 2021 October. 32:S149-S150. [Online ahead of print].
Kosmoliaptsis V, Gillett D, Bashari WA, Aloj L, Brown M, et al. [ 11 C]Metomidate PET/CT can aid decision-making in patients with primary aldosteronism. Endocrine Abstracts. 2021 October.
Chakrabarti S, Ai M, Henson FMD, St. John Smith E, Wong K, Newell K. Functional characterization of ovine dorsal root ganglion neurons reveal peripheral sensitization after osteochondral defect. eNeuro. 2021 September 20. 0237-21.2021.
Richards J, Memba R, Pavel MC, et al. Should local rather than national policy determine our approach to surgery during SARS-CoV-2?. Journal of Gastroenterology and Hepatology Research. 2021 September.
Vallier L, Muraro D, Brumm SA, Niakan KK, et al. TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells. eLife Sciences 10. 2021 August 31.
Gamble J, Mahbubani K, Saeb-Parsy K, Fitzgerald RC, Nowicki-Osuch K, O’Donovan M, et al. Molecular phenotyping reveals the identity of Barrett’s esophagus and its malignant transition. Science. 2021 August 13. Vol. 373, Issue 6556, pp. 760-767.
Chowdhury MM, Chen X, Sofat S, Coughlin P. Effects of Statin Therapy and Dose on Cardiovascular and Limb Outcomes in Peripheral Arterial Disease: A Systematic Review and Meta-analysis. European Journal of Vascular and Endovascular Surgery. 2021 August 10.
Vallier L, Tilson SG, Morell MM, Lenaerts A-S, Park SB, Hu Z, Jenkins B, Koulman A, Liang TJ. Modelling PNPLA3‐Associated Non‐Alcoholic Fatty Liver Disease Using Human Induced Pluripotent Stem Cells. Hepatology. 2021 Jul 20.
Copley CC, Gragert L, Kosmoliaptsis V, Leach AR. Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual Level. Frontiers in Immunology. 2021 Jul 19. 12:669357.
Gnanapragasam V, Sushentsev N, Rundo L, Blyuss O, Nazarenko T, Suvorov A, Sala E, Barrett T. Comparative performance of MRI-derived PRECISE scores and delta-radiomics models for the prediction of prostate cancer progression in patients on active surveillance. European Radiology. 2021 Jul 13.
Wilson ECF, Wreford A, Tamer P, Leonard K, Brechka H, Gnanapragasam V. Economic Evaluation of Transperineal versus Transrectal Devices for Local Anaesthetic Prostate Biopsies. PharmacoEconomics – Open. 2021 Jul 09.
Thurtle D, Jenkins V, Freeman A, Pearson M, Recchia G, Tamer P, Leonard K, Gnanapragasam V. et al. Clinical impact of the predict prostate risk communication tool in men newly diagnosed with non-metastatic prostate cancer: A multi-centre randomised controlled trial. European Urology. 2021 Jul 08. Pages S1446-S1447. [Online ahead of print].
Light A, Keates A, Thankappannair V, Warren A, Barrett T, Gnanapragasam V. Development of the STRATified CANcer Surveillance protocol for men with favourable-risk prostate cancer. European Urology. 2021 Jul 08. Pages S1473-S1474. [Online ahead of print].
Tambur AR, Kosmoliaptsis V, Claas FHJ, Mannon RB, Nickerson P, Naesens M. Significance of HLA-DQ in kidney transplantation – Time to re-evaluate HLA matching priorities to improve transplant outcomes? An expert review and recommendations. Kidney International Reports. 2021 Jul 08. [Online ahead of print].
Loh B, Lim JA, Seah M, Khan WS. Perioperative management of open fractures in the lower limb. Journal of Perioperative Practice 2021 Jul 02 PMID: 34214004.
Sushentsev N, Rundo L, Blyuss O, Gnanapragasam VJ, Sala E, Barrett T. MRI-derived radiomics model for baseline prediction of prostate cancer progression on active surveillance. Scientific Reports 2021 Jun 21. Article number: 12917.
Richards JA, Roberts JL, Fedotovs A, Paul S, Cottee S, Defries G, Watson CJE, Pettigrew GJ. Outcomes for circulatory death and brainstem death pancreas transplantation with or without use of normothermic regional perfusion. British Journal of Surgery 2021 Jun 22.
Jochmans I, Hessheimer AJ, Neyrinck AP, Watson CJE. et al. Consensus statement on normothermic regional perfusion in donation after circulatory death: report from the European Society for Organ Transplantation’s Transplant Learning Journey. Transpl. Int. 2021 Jun 18. [Online ahead of print].
Byrne MHV, Mehmood A, Summers DM, Hosgood SA, Nicholson ML. A systematic review of living kidney donor enhanced recovery after surgery. Clinical Transplantation. 2021 Jun 08. e14384.
Carter AR, Davies BM, Brindley DA. Gazing Long into a Clinical and Social Abyss? Treating Hypertrophic Scarring and Keloids. Rejuvenation Research 2021 Jun 08. Volume 24, Number 4
Eldridge SE, Barawi A, Roelofs A, Henson FMD, De Bari C, McCaskie AW, et al. AB0039 Agrin repairs bone and cartilage in vivo. Annals of the Rheumatic Diseases. 2021 June 80(Suppl 1):1052.1-1052.
Blackmur JP, Gaba F, Fernando D, Williams S, Stewart GD. et al. Leibovich score is the optimal clinico-pathological system associated with recurrence of non-metastatic clear cell renal cell carcinoma. Urol. Oncol. 2021 May 19;S1078-1439(21)00164-2.
Light A, Burns-Cox N, Maccormick A, John J, McGrath J, Gnanapragasam VJ. The diagnostic impact of UK regional variations in age-specific prostate-specific antigen guidelines. BJU Int. 2021 May 20.
Waseem S, Lenihan J, Davies BM, Rawal J, Hull P, Carrothers A, Chou D. Low Body Mass Index is Associated with Increased Mortality in Patients with Pelvic and Acetabular Fractures. Injury Reports. 2021 May 04. [Online ahead of print]
Dolezalova N, Gruszczyk A, Barkan K, Gamble JA, Mahbubani KT, Higgins JA, Saeb-Parsy K, et al. Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets. Sc Rep. 2021 May 17;11(1):10418.
Kamaraj A, Agarwal N, Agarwal, Seah KTM, Khan WS. Understanding cost-utility analysis studies in the trauma and orthopaedic surgery literature. EFORT Open Reviews 2021 May;6(5)
Corrie PG, Welsh SJ, Stewart GD, et al. Identification of a microbiome signature predicting immune checkpoint inhibitor outcomes across multiple cancer types in the MITRE study. Journal of Clinical Oncology 2021 May; 39(15_suppl):TPS2665-TPS2665
Dokubo II, Reeves F, Cashman S, Gnanapragasam VJ. Rationalising the use of investigation for urinary tract infections: Analysis of 700 patients and proposal for a diagnostic algorithm. Int J Clin Pract. 2021 May;75(5):e13977.
Steinberg J, Southam L, Fontalis A, Clark MJ, Jayasuriya RL, Swift D, Shah KM, Brooks RA, McCaskie AW, Wilkinson JM, Zeggini E. Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis. Ann Rheum Dis. 2021 Apr 26;annrheumdis-2020-219760 [Online ahead of print]
Greenhall GHB, Robb M, Brown C, Johnson R, Tomlinson LA, Callaghan CJ, Watson CJE. Solid Organ Transplantation From Deceased Donors With Infective Endocarditis: The UK Experience. Transplantation. 2021 Apr 21. [Online ahead of print]
Abu-Ghanem Y, Powles T, Capitanio U, Beisland C, Järvinen P, Stewart GD et al. Should patients with low risk renal cell carcinoma be followed differently after nephron‐sparing surgery vs radical nephrectomy? BJU Int. 2021 Apr 1. [Online ahead of print]
Sokal DM, McSloy A, Donegà M, Kirk J, Colas RA, Dolezalova N et al. Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs. Front Immunol. 2021 Mar 29;12:649786.
COVIDSurg Collaborative (incl G.D. Stewart). SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg. 2021 Mar 24;znab101. [Online ahead of print]
Van Hemelrijck M, Ji X, Helleman J, Roobol MJ, Gnanapragasam V et al. A first step towards a global nomogram to predict disease progression for men on active surveillance. Transl Androl Urol. 2021 Mar;10(3):1102-1109.
COVIDSurg Collaborative (incl G.D. Stewart, dissemination committee). Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia. 2021 Mar 9. [Online ahead of print]
Lee C, Light A, Alaa A, Thurtle D, van der Schaar M, Gnanapragasam VJ. Application of a novel machine learning framework for predicting non-metastatic prostate cancer-specific mortality in men using the Surveillance, Epidemiology, and End Results (SEER) database. Lancet Digit Health. 2021 Mar;3(3):e158-e165.
Liu S, Shen M, Hsu EC, Zhang CA, Garcia-Marques F, Gnanapragasam VJ, Stoyanova T et al. Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer. Br J Cancer. 2021 Mar;124(5):896-900.
Sutton E, Lane JA, Davis M, Walsh EI, Neal DE, Hamdy FC, Mason M, Staffurth J, Martin RM, Metcalfe C, Peters TJ, Donovan JL, Wade J; ProtecT Study Group (Gnanapragsam VJ). Men’s experiences of radiotherapy treatment for localized prostate cancer and its long-term treatment side effects: a longitudinal qualitative study. Cancer Causes Control. 2021 Mar;32(3):261-269.
COVIDSurg Collaborative (incl G.D. Stewart, writing group). Elective cancer surgery in COVID-19 free surgical pathways during the SARS-CoV-2 pandemic: An international, multi-centre, comparative cohort study. Journal of Clinical Oncology. 2021;39(1):66-78.
Steinberg J, Southam L, Roumeliotis TI, Brooks RA, McCaskie AW et al. Nature Commun. 2021 Feb 26;12(1):1309.
Kuusk T, Klatte T, Stewart GD, et al. Outcome after resection of occult and non-occult lymph node metastases at the time of nephrectomy. World J Urol. 2021 Feb 25. [Online ahead of print]
Bruinsma SM, Nieboer D, Gnanapragasam V, et al. Risk-Based Selection for Active Surveillance: Results of the Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance (GAP3) Initiative. J Urol. 2021 Feb 22;101097JU0000000000001700. [Online ahead of print]
Anderton J, Ghobrial M, Kosmoliaptsis V, Casey R. Large adrenal mass heralding the diagnosis of occult extra-adrenal malignancy in two patients. BMJ Case Rep. 2021 Feb 22;14(2):e239463.
MacKay JW, Nezhad FS, Rifai T, Kaggie JD, Naish JH, Roberts C, Graves MJ, Waterton JC, Janiczek RL, Roberts AR, McCaskie A, Gilbert FJ, Parker GJM. Dynamic contrast-enhanced MRI of synovitis in knee osteoarthritis: repeatability, discrimination and sensitivity to change in a prospective experimental study. Eur Radiol. 2021 Feb 16. [Online ahead of print]
Ecke TH, Schwaiger D, Nesterov G, Koswig S, Selinski S, Barrett T, Gnanapragasam V et al . Comparison of initial and second opinion reads of multiparametric magnetic resonance imaging of the prostate for transperineal template-guided biopsies with MRI-Ultrasound fusion. Urol Oncol. 2021 Feb 6:S1078-1439(21)00007-7.
Richards JA, Gaurav R, Upponi SS, Watson CJE, Butler AJ. Machine Perfusion-Leaving Its Mark on Liver Transplantation. Transplantation 2021 Feb 1;105(2):e28-e29.
Stewart GD, Welsh S, Ursprung S, et al. NAXIVA: A phase II neoadjuvant study of axitinib for reducing extent of venous tumor thrombus in clear cell renal cell cancer (RCC) with venous invasion. Journal of Clinical Oncology. 2021 Feb. 39(6_suppl):275-275
Agarwal N, To K, Khan WS. Cost effectiveness analyses of total hip arthroplasty for hip osteoarthritis: A PRISMA systematic review. Int J Clin Pract. 2021 Feb;75(2):e13806
Chan CD, Haagensen EJ, Tensaout HA, Rennie KJ, Gamie Z, Barry J, Birch MA, Gerrand CH. Co localisation of intra nuclear membrane type 1 matrix metalloproteinase and hypoxia inducible factor 2α in osteosarcoma and prostate carcinoma cells. Oncology Letters. 2021 21(2):1–1.
Richards JA, Randle LV, Butler AJ, Martin JL, Fedotovs A, Davies SE, Watson CJE, Robertson PA. Clinical trial of a real-time optical backscatter probe predicts liver transplantation outcomes. Transpl. Int 2021 Jan 19. [Online ahead of print]
Richards J, Gimson A, Joh Y, Watson C, Neuberger J. Trials & Tribulations of Liver Transplantation- are trials now prohibitive without surrogate endpoints? Liver transpl. 2021 Jan 19. [Online ahead of print]
Tomlinson F, Terschuur J, Henson FMD. Use of autologous products for the treatment of joint and soft tissue disease in horses: A systematic review. The Veterinary record. 2021 Jan; 188(2)
