2021
Chakrabarti S, Ai M, Henson FMD, St. John Smith E, Wong K, Newell K. Functional characterization of ovine dorsal root ganglion neurons reveal peripheral sensitization after osteochondral defect. eNeuro. 2021 September 20. 0237-21.2021.
Vallier L, Muraro D, Brumm SA, Niakan KK, et al. TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells. eLife Sciences 10. 2021 August 31.
Gamble J, Mahbubani K, Saeb-Parsy K, Fitzgerald RC, Nowicki-Osuch K, O’Donovan M, et al. Molecular phenotyping reveals the identity of Barrett’s esophagus and its malignant transition. Science. 2021 August 13. Vol. 373, Issue 6556, pp. 760-767.
Chowdhury MM, Chen X, Sofat S, Coughlin P. Effects of Statin Therapy and Dose on Cardiovascular and Limb Outcomes in Peripheral Arterial Disease: A Systematic Review and Meta-analysis. European Journal of Vascular and Endovascular Surgery. 2021 August 10.
Vallier L, Tilson SG, Morell MM, Lenaerts A-S, Park SB, Hu Z, Jenkins B, Koulman A, Liang TJ. Modelling PNPLA3‐Associated Non‐Alcoholic Fatty Liver Disease Using Human Induced Pluripotent Stem Cells. Hepatology. 2021 Jul 20.
Copley CC, Gragert L, Kosmoliaptsis V, Leach AR. Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual Level. Frontiers in Immunology. 2021 Jul 19. 12:669357.
Gnanapragasam V, Sushentsev N, Rundo L, Blyuss O, Nazarenko T, Suvorov A, Sala E, Barrett T. Comparative performance of MRI-derived PRECISE scores and delta-radiomics models for the prediction of prostate cancer progression in patients on active surveillance. European Radiology. 2021 Jul 13.
Wilson ECF, Wreford A, Tamer P, Leonard K, Brechka H, Gnanapragasam V. Economic Evaluation of Transperineal versus Transrectal Devices for Local Anaesthetic Prostate Biopsies. PharmacoEconomics – Open. 2021 Jul 09.
Thurtle D, Jenkins V, Freeman A, Pearson M, Recchia G, Tamer P, Leonard K, Gnanapragasam V. et al. Clinical impact of the predict prostate risk communication tool in men newly diagnosed with non-metastatic prostate cancer: A multi-centre randomised controlled trial. European Urology. 2021 Jul 08. Pages S1446-S1447. [Online ahead of print].
Light A, Keates A, Thankappannair V, Warren A, Barrett T, Gnanapragasam V. Development of the STRATified CANcer Surveillance protocol for men with favourable-risk prostate cancer. European Urology. 2021 Jul 08. Pages S1473-S1474. [Online ahead of print].
Tambur AR, Kosmoliaptsis V, Claas FHJ, Mannon RB, Nickerson P, Naesens M. Significance of HLA-DQ in kidney transplantation – Time to re-evaluate HLA matching priorities to improve transplant outcomes? An expert review and recommendations. Kidney International Reports. 2021 Jul 08. [Online ahead of print].
Loh B, Lim JA, Seah M, Khan WS. Perioperative management of open fractures in the lower limb. Journal of Perioperative Practice 2021 Jul 02 PMID: 34214004.
Sushentsev N, Rundo L, Blyuss O, Gnanapragasam VJ, Sala E, Barrett T. MRI-derived radiomics model for baseline prediction of prostate cancer progression on active surveillance. Scientific Reports 2021 Jun 21. Article number: 12917.
Richards JA, Roberts JL, Fedotovs A, Paul S, Cottee S, Defries G, Watson CJE, Pettigrew GJ. Outcomes for circulatory death and brainstem death pancreas transplantation with or without use of normothermic regional perfusion. British Journal of Surgery 2021 Jun 22.
Jochmans I, Hessheimer AJ, Neyrinck AP, Watson CJE. et al. Consensus statement on normothermic regional perfusion in donation after circulatory death: report from the European Society for Organ Transplantation’s Transplant Learning Journey. Transpl. Int. 2021 Jun 18. [Online ahead of print].
Byrne MHV, Mehmood A, Summers DM, Hosgood SA, Nicholson ML. A systematic review of living kidney donor enhanced recovery after surgery. Clinical Transplantation. 2021 Jun 08. e14384.
Carter AR, Davies BM, Brindley DA. Gazing Long into a Clinical and Social Abyss? Treating Hypertrophic Scarring and Keloids. Rejuvenation Research 2021 Jun 08. Volume 24, Number 4
Eldridge SE, Barawi A, Roelofs A, Henson FMD, De Bari C, McCaskie AW, et al. AB0039 Agrin repairs bone and cartilage in vivo. Annals of the Rheumatic Diseases. 2021 June 80(Suppl 1):1052.1-1052.
Blackmur JP, Gaba F, Fernando D, Williams S, Stewart GD. et al. Leibovich score is the optimal clinico-pathological system associated with recurrence of non-metastatic clear cell renal cell carcinoma. Urol. Oncol. 2021 May 19;S1078-1439(21)00164-2.
Light A, Burns-Cox N, Maccormick A, John J, McGrath J, Gnanapragasam VJ. The diagnostic impact of UK regional variations in age-specific prostate-specific antigen guidelines. BJU Int. 2021 May 20.
Waseem S, Lenihan J, Davies BM, Rawal J, Hull P, Carrothers A, Chou D. Low Body Mass Index is Associated with Increased Mortality in Patients with Pelvic and Acetabular Fractures. Injury Reports. 2021 May 04. [Online ahead of print]
Dolezalova N, Gruszczyk A, Barkan K, Gamble JA, Mahbubani KT, Higgins JA, Saeb-Parsy K, et al. Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets. Sc Rep. 2021 May 17;11(1):10418.
Kamaraj A, Agarwal N, Agarwal, Seah KTM, Khan WS. Understanding cost-utility analysis studies in the trauma and orthopaedic surgery literature. EFORT Open Reviews 2021 May;6(5)
Corrie PG, Welsh SJ, Stewart GD, et al. Identification of a microbiome signature predicting immune checkpoint inhibitor outcomes across multiple cancer types in the MITRE study. Journal of Clinical Oncology 2021 May; 39(15_suppl):TPS2665-TPS2665
Dokubo II, Reeves F, Cashman S, Gnanapragasam VJ. Rationalising the use of investigation for urinary tract infections: Analysis of 700 patients and proposal for a diagnostic algorithm. Int J Clin Pract. 2021 May;75(5):e13977.
Steinberg J, Southam L, Fontalis A, Clark MJ, Jayasuriya RL, Swift D, Shah KM, Brooks RA, McCaskie AW, Wilkinson JM, Zeggini E. Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis. Ann Rheum Dis. 2021 Apr 26;annrheumdis-2020-219760 [Online ahead of print]
Greenhall GHB, Robb M, Brown C, Johnson R, Tomlinson LA, Callaghan CJ, Watson CJE. Solid Organ Transplantation From Deceased Donors With Infective Endocarditis: The UK Experience. Transplantation. 2021 Apr 21. [Online ahead of print]
Abu-Ghanem Y, Powles T, Capitanio U, Beisland C, Järvinen P, Stewart GD et al. Should patients with low risk renal cell carcinoma be followed differently after nephron‐sparing surgery vs radical nephrectomy? BJU Int. 2021 Apr 1. [Online ahead of print]
Sokal DM, McSloy A, Donegà M, Kirk J, Colas RA, Dolezalova N et al. Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs. Front Immunol. 2021 Mar 29;12:649786.
COVIDSurg Collaborative (incl G.D. Stewart). SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg. 2021 Mar 24;znab101. [Online ahead of print]
Van Hemelrijck M, Ji X, Helleman J, Roobol MJ, Gnanapragasam V et al. A first step towards a global nomogram to predict disease progression for men on active surveillance. Transl Androl Urol. 2021 Mar;10(3):1102-1109.
COVIDSurg Collaborative (incl G.D. Stewart, dissemination committee). Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia. 2021 Mar 9. [Online ahead of print]
Lee C, Light A, Alaa A, Thurtle D, van der Schaar M, Gnanapragasam VJ. Application of a novel machine learning framework for predicting non-metastatic prostate cancer-specific mortality in men using the Surveillance, Epidemiology, and End Results (SEER) database. Lancet Digit Health. 2021 Mar;3(3):e158-e165.
Liu S, Shen M, Hsu EC, Zhang CA, Garcia-Marques F, Gnanapragasam VJ, Stoyanova T et al. Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer. Br J Cancer. 2021 Mar;124(5):896-900.
Sutton E, Lane JA, Davis M, Walsh EI, Neal DE, Hamdy FC, Mason M, Staffurth J, Martin RM, Metcalfe C, Peters TJ, Donovan JL, Wade J; ProtecT Study Group (Gnanapragsam VJ). Men’s experiences of radiotherapy treatment for localized prostate cancer and its long-term treatment side effects: a longitudinal qualitative study. Cancer Causes Control. 2021 Mar;32(3):261-269.
COVIDSurg Collaborative (incl G.D. Stewart, writing group). Elective cancer surgery in COVID-19 free surgical pathways during the SARS-CoV-2 pandemic: An international, multi-centre, comparative cohort study. Journal of Clinical Oncology. 2021;39(1):66-78.
Steinberg J, Southam L, Roumeliotis TI, Brooks RA, McCaskie AW et al. Nature Commun. 2021 Feb 26;12(1):1309.
Kuusk T, Klatte T, Stewart GD, et al. Outcome after resection of occult and non-occult lymph node metastases at the time of nephrectomy. World J Urol. 2021 Feb 25. [Online ahead of print]
Bruinsma SM, Nieboer D, Gnanapragasam V, et al. Risk-Based Selection for Active Surveillance: Results of the Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance (GAP3) Initiative. J Urol. 2021 Feb 22;101097JU0000000000001700. [Online ahead of print]
Anderton J, Ghobrial M, Kosmoliaptsis V, Casey R. Large adrenal mass heralding the diagnosis of occult extra-adrenal malignancy in two patients. BMJ Case Rep. 2021 Feb 22;14(2):e239463.
MacKay JW, Nezhad FS, Rifai T, Kaggie JD, Naish JH, Roberts C, Graves MJ, Waterton JC, Janiczek RL, Roberts AR, McCaskie A, Gilbert FJ, Parker GJM. Dynamic contrast-enhanced MRI of synovitis in knee osteoarthritis: repeatability, discrimination and sensitivity to change in a prospective experimental study. Eur Radiol. 2021 Feb 16. [Online ahead of print]
Ecke TH, Schwaiger D, Nesterov G, Koswig S, Selinski S, Barrett T, Gnanapragasam V et al . Comparison of initial and second opinion reads of multiparametric magnetic resonance imaging of the prostate for transperineal template-guided biopsies with MRI-Ultrasound fusion. Urol Oncol. 2021 Feb 6:S1078-1439(21)00007-7.
Richards JA, Gaurav R, Upponi SS, Watson CJE, Butler AJ. Machine Perfusion-Leaving Its Mark on Liver Transplantation. Transplantation 2021 Feb 1;105(2):e28-e29.
Stewart GD, Welsh S, Ursprung S, et al. NAXIVA: A phase II neoadjuvant study of axitinib for reducing extent of venous tumor thrombus in clear cell renal cell cancer (RCC) with venous invasion. Journal of Clinical Oncology. 2021 Feb. 39(6_suppl):275-275
Agarwal N, To K, Khan WS. Cost effectiveness analyses of total hip arthroplasty for hip osteoarthritis: A PRISMA systematic review. Int J Clin Pract. 2021 Feb;75(2):e13806
Chan CD, Haagensen EJ, Tensaout HA, Rennie KJ, Gamie Z, Barry J, Birch MA, Gerrand CH. Co localisation of intra nuclear membrane type 1 matrix metalloproteinase and hypoxia inducible factor 2α in osteosarcoma and prostate carcinoma cells. Oncology Letters. 2021 21(2):1–1.
Richards JA, Randle LV, Butler AJ, Martin JL, Fedotovs A, Davies SE, Watson CJE, Robertson PA. Clinical trial of a real-time optical backscatter probe predicts liver transplantation outcomes. Transpl. Int 2021 Jan 19. [Online ahead of print]
Richards J, Gimson A, Joh Y, Watson C, Neuberger J. Trials & Tribulations of Liver Transplantation- are trials now prohibitive without surrogate endpoints? Liver transpl. 2021 Jan 19. [Online ahead of print]
Tomlinson F, Terschuur J, Henson FMD. Use of autologous products for the treatment of joint and soft tissue disease in horses: A systematic review. The Veterinary record. 2021 Jan; 188(2)
2020
Bottle A, Griffiths R, White S, Davies BM, et al. Periprosthetic fractures: the next fragility fracture epidemic? A national observational study. BMJ Open. 2020 Dec 10;10(12):e042371.
Eisen T, Frangou E, Oza B, Stewart GD, et al. Adjuvant Sorafenib for Renal Cell Carcinoma at Intermediate or High Risk of Relapse: Results From the SORCE Randomized Phase III Intergroup Trial. J. Clin. Oncol. 2020 Dec 1;38(34):4064-4075.
Sushentsev N, Kaggie JD, Buonincontri G, Schulte RF, Graves MJ, Gnanapragasam VJ, Barrett T. The effect of gadolinium-based contrast agent administration on magnetic resonance fingerprinting-based T 1 relaxometry in patients with prostate cancer. Sci Rep. 2020 Nov 24;10(1):20475.
Caglic I, Sushentsev N, Gnanapragasam VJ, et al. MRI-derived PRECISE scores for predicting pathologically-confirmed radiological progression in prostate cancer patients on active surveillance. Our Radiol. 2020 Nov 16. [Online ahead of print]
Henson F, Lydon H, Birch M, Brooks R, McCaskie A. Using apheresis-derived cells to augment microdrilling in the treatment of chondral defects in an ovine model. J Orthop Res. 2020 Nov 4. [Online ahead of print]
Matas‐Céspedes A, Brown L, Mahbubani K, Saeb-Parsy K et al. Use of human splenocytes in an innovative humanised mouse model for prediction of immunotherapy‐induced cytokine release syndrome. Clinical & Translational Immunology. 2020 Nov 4; 9(e1202)
Henson F, Lydon H, Birch MA, Brooks R, McCaskie AW. Using apheresis-derived cells to augment microdrilling in the treatment of chondral defects in an ovine model. Journal of Orthopaedic Research 2020 Nov 4. [Online ahead of print]
Agarwal N, To K, Mcdonnell S, Khan WS. Clinical and radiological outcomes in robotic assisted total knee arthroplasty: a systematic review and meta-analysis. Journal of Arthroplasty Volume 35, Issue 11, November 2020, Pages 3393-3409.e2.
Gupta I, Cassará AM, Tarotin I, Donega M, Dolezalova N, Saeb-Parsy K, et al. Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves. Commun Biol. 2020 Oct 16;3(1):577.
Kamaraj A, To K, Seah M, Khan WS. Modelling the cost-effectiveness of total knee arthroplasty: A systematic review. J Ortho. 2020 Oct 8;22:485-492.
Cunniffe NG, Gunter SJ, Brown M, Stewart GD, et al. How achievable are COVID-19 clinical trial recruitment targets? A UK observational cohort study and trials registry analysis. BMJ Open 2020 Oct 5;10(10):e044566.
Lawson ARJ, Abascal F, Mahbubani KT, Bareham B, Gnanapragasam V, Saeb-Parsy K, Mitchell T, et al. Extensive heterogeneity in somatic mutation and selection in the human bladder. Science. 2020 Oct 2;Vol. 370, Issue 6512, pp. 75-82.
Guldvik IJ, Zuber V, Braadland PR, Gnanapragasam V, et al. Identification and Validation of Leucine-rich a-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification. European Urology Open Science. 2020 Oct; Vol.21:51-60
Atici SD, Kaya T, Aydin C, Stewart GD, et al. Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic. British Journal of Surgery 2020 Oct
Litviňuková M, Talavera-López C, Maatz H, Saeb-Parsy K, Mahbubani KT, et al. Cells of the adult human heart. Nature. 2020 Sep 24. [Online ahead of print]
Jordan NP, Nicholson ML, Hosgood SA. MicroRNA-126-3p is Downregulated in Human Kidneys in a Model of Reperfusion Injury. Kidney International Reports. 2020 Sep 23;5(12) P2357-2360.
Saeb-Parsy K, Martin JL, Summers DM, Watson CJE, Krieg T, Murphy MP. Mitochondria as Therapeutic Targets in Transplantation. Trends Mol Med. 2020 Sep 17;S1471-4914(20)30190-8. [Online ahead of print]
Mostafa AMHAM, Kyriacou H, Chimutengwende-Gordon M, Khan WS. An overview of the key principles and guidelines in the management of pelvic fractures. J Perioper Pract. 2020 Sep 8;1750458920947358.
Lim JA, Loh B, Sylvestor G, Khan W. Perioperative management of distal radius fractures. J Perioper Pract. 2020 Sep 8;1750458920949463. [Online ahead of print]
Eldridge SE, Barawi A, Wang H, Roelofs A, Henson F, McCaskie AM, De Bari C, et al. Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis. Science Translational Medicine. 2020 Sep 2;12(559) eaax9086
Crispin-Ortuzar M, Gehrung M, Ursprung S, Stewart G, Mitchell T, et al. Three-Dimensional Printed Molds for Image-Guided Surgical Biopsies: An Open Source Computational Platform Licensed under the Creative Commons Attribution 4.0 License. JCO Clinical Cancer Informatics. August 2020; 4(4):736-748
Seefried L, Blyth M, Maheshwari R, McDonnell SM, et al. Penetration of topical diclofenac into synovial tissue and fluid of osteoarthritic knees: a multicenter, randomized, placebo-controlled, pharmacokinetic study. Ther Adv Musculoskelet Dis. 2020 Aug 29;12:1759720X20943088. eCollection 2020.
Usher-Smith J, Simmons RK, Rossi S, Stewart GD. Current evidence on screening for renal cancer. Nature Reviews Urology. 2020 Aug 28 [online]
Darst BF, Dadaev T, Saunders EJ, Gnanapragasam VJ et al. Germline sequencing DNA repair genes in 5,545 men with aggressive and non-aggressive prostate cancer. J Natl Cancer Inst. 2020 Aug 27;djaa132. [Online ahead of print]
Prag HA, Gruszczyk AV, Huang MM, Beach TE, Saeb-Parsy K et al. Mechanism of succinate efflux upon reperfusion of the ischemic heart. Cardiovasc Research. 2020 Aug 7;cvaa148. [Online ahead of print]
Chakrabarti S, Ai M, Henson FMD, St. John Smith E. Peripheral mechanisms of arthritic pain: A proposal to leverage large animals for in vitro studies. Neurobiology of Pain. 2020 July 28. [Epub]
Noble S, Garfield K, Gnanapragasam VJ et al. The ProtecT randomised trial cost-effectiveness analysis comparing active monitoring, surgery, or radiotherapy for prostate cancer. Br J Cancer. 2020 Jul 16 [Epub ahead of print]
Harrison H, Thompson RE, Lin Z, Rossi SH, Stewart GD, Griffin SJ, Usher-Smith JA. Risk Prediction Models for Kidney Cancer: A Systematic Review. Eur Urol Focus. 2020 Jul 14:S2405-4569(20)30190-5 [Epub ahead of print]
Prag HA, Pala L, Kula-Alwar D, Saeb-Parsy K, Beach TE, et al. Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo. Cardiovasc Drugs Ther. 2020 July 9 [Epub ahead of print]
Bentley S, Johnson C, Exall E, Brohan E, Lawrance R, Bennett B, Bargo D, Zanotti G, Staehler M, Stewart G. Improving patient-clinician communication following nephrectomy in Renal Cell Carcinoma: Development, content validation and pilot testing of a Conversation Aid Tool. Patient Education and Counseling. 2020 June 30 [online]
Ayorinde JOO, Saeb-Parsy K, Hossain A. Opportunities and Challenges in Using Social Media in Organ Donation. JAMA Surg. 2020 June 17 [online]
Wan JCM, Stewart GD et al. ctDNA Monitoring Using Patient-Specific Sequencing and Integration of Variant Reads Sci Transl Med. 2020 Jun 17;12(548):eaaz8084.
Thurtle D, Bratt Ola, Stattin P, Pharoah P, Gnanapragasam VJ. Comparative performance and external validation of the multivariable PREDICT Prostate tool for non-metastatic prostate cancer: A study in 69,206 men from Prostate Cancer data Base Sweden (PCBaSe). BMC Med. 2020 Jun 16;18(1):139.
Gnanapragasam VJ, Leonard K, Sut M, Ilie C, Ord J, Roux J, Prieto MCH, Warren A, Tamer P. Multicentre clinical evaluation of the safety and performance of a simple transperineal access system for prostate biopsies for suspected prostate cancer: The CAMbridge PROstate Biopsy DevicE (CamPROBE) study. Journal of Clinical Urology. 2020 June 12 [Epub ahead of print]
To K, Romain K, Mak C, Kamaraj A, Henson F, Khan W. The Treatment of Cartilage Damage Using Human Mesenchymal Stem Cell-Derived Extracellular Vesicles: A Systematic Review of in vivo Studies. Front Bioeng Biotechnol 2020 Jun 11;8:580. [eCollection 2020]
Zawaideh JP, Sala E, Pantelidou M, Shaida N, Koo B, Caglic I, Warren AY, Carmisciano L, Saeb-Parsy K, Gnanapragasam VJ, Kastner C, Barrett T. Comparison of Likert and PI-RADS Version 2 MRI Scoring Systems for the Detection of Clinically Significant Prostate Cancer. Radiol. 2020 Jun 1;20200298. [Epub ahead of print]
Migliorini F, Berton A, Salvatore G, Candela V, Khan WS, Longo UG, Denaro V. Autologous chondrocyte implantation and mesenchymal stem cells for the treatments of chondral defects of the knee- a systematic review. Curr Stem Cell Res Ther. 2020;15(6):547-556.
Basyuni S, Ferro A, Santhanam V, Birch MA, McCaskie AW. Systematic scoping review of mandibular bone tissue engineering. Br J Oral Maxillofac Surg . 2020 58(6) 632-642.
Parry MG, Cowling TE, Sujenthiran A, Nossiter J, Berry B, Cathcart P, Aggarwal A, Payne H, van der Meulen J, Clarke NW, Gnanapragasam VJ. Risk stratification for prostate cancer management: value of the Cambridge Prognostic Group. BMC Med. 2020 May 28;18(1):114.
Kaggie JD, Markides H, Graves MJ, MacKay J, Houston G, El Haj A, Gilbert F, Henson FMD. Ultra Short Echo Time MRI of Iron-Labelled Mesenchymal Stem Cells in an Ovine Osteochondral Defect Model. Sci Rep. 2020 May 21;10(1):8451.
Paterson YZ, Cribbs A, Espenel M, Smith EJ, Henson FMD, Guest DJ. Genome-wide transcriptome analysis reveals equine embryonic stem cell-derived tenocytes resemble fetal, not adult tenocytes. Stem Cell Research & Therapy 2020 May 19;11(184)
Green M, Byrne MHV, Legard C, Chen E, Critchley A, Stainer B, Chaggar H, Symington M, Hu L, Brathwaite-Shirley C, Mayes J, Mogg JAW, Murphy J, Saeb-Parsy K. The Effect of Positive and Negative Poster Messages on Organ Donor Registration. Transplant Proc. 2020 May 16:S0041-1345(20)30280-3.[Epub ahead of print]
Chisari E, Rehak L, Khan WS, Maffulli N. The Role of the Immune System in Tendon Healing: A Systematic Review. Br Med Bull. 2020 May 15;133(1):49-64.
Ranmuthu CDS, Ranmuthu CKI, Russell JC, Singhania D, Khan WS. Evaluating the Effect of Non-cellular Bioactive Glass-Containing Scaffolds on Osteogenesis and Angiogenesis in in vivo Animal Bone Defect Models. Front Bioeng Biotechnol. 2020 May 14;8:430.
Tambur AR, Campbell P, Chong AS, Feng S, Ford ML, Gebel H, Gill RG, Kelsoe G, Kosmoliaptsis V, Mannon RB, Mengel M, Reed EF, Valenzuela NM, Wiebe C, Dijke E, Sullivan HC, Nickerson P. Sensitization in Transplantation: Assessment of Risk (STAR) 2019 Working Group Meeting Report. Am J Transplant. 2020 Apr 27. [Epub ahead of print]
Bojanic C, To K, Zhang B, Mak C, Khan WS. Human umbilical cord derived mesenchymal stem cells in peripheral nerve regeneration. World J Stem Cells. 2020 Apr 26;12(4):288-302.
Sungnak W, Huang N, Bécavin C, Berg M, Queen R, Litvinukova M, Talavera-López C, Maatz H, Reichart D, Sampaziotis F, Worlock KB, Yoshida M, Barnes JL; HCA Lung Biological Network. SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nat Med. 2020 Apr 23. [Epub ahead of print]
Wajs E, Rughoobur G, Burling K, George A, Flewitt A, Gnanapragasam V. A novel split mode TFBAR devices for quantitative measurements of prostate specific antigen in a small sample of whole blood. Nanoscale. 2020 May 7;12(17):9647-9652. Epub 2020 Apr 22.
Moore L, Leongamornlert D, Coorens THH, Sanders MA, Ellis P, Dentro SC, Dawson KJ, Butler T, Rahbari R, Mitchell TJ, Maura F, Nangalia J, Tarpey PS, Brunner SF, Lee-Six H, Hooks Y, Moody S, Mahbubani KT, Jimenez-Linan M, Brosens JJ, Iacobuzio-Donahue CA, Martincorena I, Saeb-Parsy K, Campbell PJ, Stratton MR. The mutational landscape of normal human endometrial epithelium. Nature. 2020 Apr;580(7805):640-646. [Epub 2020 Apr 22]. press release
Kim L, Boxall N, George A, Burling K, Acher P, Aning J, McCracken S, Page T, Gnanapragasam VJ. Clinical utility and cost modelling of the phi test to triage referrals into image-based diagnostic services for suspected prostate cancer: the PRIM (Phi to RefIne Mri) study. BMC Med. (2020) IF 8.3 Apr 17;18(1):95
Kyriacou H, Khan WS. Important perioperative factors, guidelines and outcomes in the management of hip fracture. J Perioper Pract. 2020 Apr 17:1750458920915656.
Al-Lamki RS, Hudson NJ, Bradley JR, Warren AY, Eisen T, Welsh SJ, Riddick ACP, O’Mahony FC, Turnbull A, Powles T, Scotrrcc Collaborative, Reverter A, Harrison DJ, Stewart GD. The Efficacy of Sunitinib Treatment of Renal Cancer Cells Is Associated with the Protein PHAX In Vitro. Biology (Basel). 2020 Apr 7;9(4). pii: E74.
Hemelrijck MV, Ji X, Helleman J, Roobol M, Nieboer D, Bangma C, Frydenberg M, Rannikko A, Lee LS, Gnanapragasam V, Kattan M and GAP3 Movember Foundation’s Active Surveillance Database. PD62-01 A first step towards a global nomogram to predict disease progression for men on active surveillance. Journal of Urology 2020 April 1; vol.203, Issue Supplement 4
Ellis RJ, Del Vecchio SJ, Gallagher KMJ, Aliano DN, Barber N, Bolton DM, Chew ETS, Coombes JS, Coory MD, Davis ID, Donaldson JF, Francis RS, Giles GG, Gobe GC, Hawley CM, Johnson DW, Laird A, Leung S, Malki M, Marco DJT, McNeill AS, Neale RE, Ng KL, Phipps S, Stewart GD, White VM, Wood ST, Jordan SJ. A Simple Clinical Tool for Stratifying Risk of Clinically Significant CKD after Nephrectomy: Development and Multinational Validation. JASN 2020 April; ASN.2019121328
JW MacKay, TD Turmezei, J Kaggie, AR Morgan, R Janiczek, WS Khan, S McDonnell, MJ Graves. Three-dimensional Surface-based Analysis of Cartilage MRI data in Knee Osteoarthritis: Validation and Initial Clinical Application. JMRI 2020 52(4):1139-1151. PMID: 32447815
Hotham WE, Henson FMD. The use of large animals to facilitate the process of MSC going from laboratory to patient-‘bench to bedside’. Cell Biology and Toxicology. 2020 Mar 23 [Epub]
Zawaideh JP, Sala E, Shaida N. Koo B, Warren AY, Carmisciano L, Saeb-Parsy K, Gnanapragasam VJ, Kastner C, Barrett T. Diagnostic accuracy of biparametric versus multiparametric prostate MRI: assessment of contrast benefit in clinical practice. Eur Radiol 2020 March 12; [Epub]
Watson CJE, Johnson RJ, Mumford L. Overview of the Evolution of the UK Kidney Allocation Schemes. Curr Transpl Rep. 2020 March 12; [Epub]
Thomas BC, Slack M, Hussain M, Barber N, Pradhan A, Dinneen E, Stewart GD. Preclinical Evaluation of the Versius Surgical System, a New Robot-assisted Surgical Device for Use in Minimal Access Renal and Prostate Surgery. Eur Urol Focus. 2020 Mar 10. pii: S2405-4569(20)30029-8. [Epub ahead of print]
Park JE, Botting RA, Domínguez Conde C, Popescu DM, Lavaert M, Kunz DJ, Goh I, Stephenson E, Ragazzini R, Tuck E, Wilbrey-Clark A, Roberts K, Kedlian VR, Ferdinand JR, He X, Webb S, Maunder D, Vandamme N, Mahbubani KT, Polanski K, Mamanova L, Bolt L, Crossland D, de Rita F, Fuller A, Filby A, Reynolds G, Dixon D, Saeb-Parsy K, Lisgo S, Henderson D, Vento-Tormo R, Bayraktar OA, Barker RA10, Meyer KB, Saeys Y, Bonfanti P, Behjati S, Clatworthy MR, Taghon T1, Haniffa M, Teichmann SA. A cell atlas of human thymic development defines T cell repertoire formation. Science. 2020 Feb 21;367(6480). pii: eaay3224.
James KR, Gomes T, Elmentaite R, Kumar N, Gulliver EL, King HW, Stares MD, Bareham BR, Ferdinand JR, Petrova VN, Polański K, Forster SC, Jarvis LB, Suchanek O, Howlett S, James LK, Jones JL, Meyer KB, Clatworthy MR, Saeb-Parsy K, Lawley TD, Teichmann SA Distinct microbial and immune niches of the human colon. Nat Immunol. 2020 Feb 17. [Epub ahead of print]
Yong C, Stewart GD. Transcriptomic Signatures Related to the Obesity Paradox in Patients with Clear Cell Renal Cell Carcinoma: A Cohort Study. Eur Urol. 2020 Feb 12. pii: S0302-2838(20)30069-5. [Epub ahead of print]
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium. Pan-cancer analysis of whole genomes. Nature. 2020 Feb;578(7793):82-93. (Co-authors: Gnanapragasam VJ, Mitchell T.)
Kwan H, Chisari E, Khan WS. Cell-Free Scaffolds as a Monotherapy for Focal Chondral Knee Defects. Materials (Basel). 2020 13(2): E306. PMID: 31936591
Noorani A, Li X, Goddard M, Crawte J, Alexandrov LB, Secrier M, Eldridge MD, Bower L, Weaver J, Lao-Sirieix P, Martincorena I, Debiram-Beecham I, Grehan N, MacRae S, Malhotra S, Miremadi A, Thomas T, Galbraith S, Petersen L, Preston SD, Gilligan D, Hindmarsh A, Hardwick RH, Stratton MR, Wedge DC, Fitzgerald RC. Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma. Nat Genet. 2020 Jan;52(1):74-83. online aticle
Sushentsev N, Caglic I, Sala E, Shaida N, Slough RA, Carmo B, Kozlov V, Gnanapragasam V, Barrett T. The effect of capped biparametric magnetic resonance imaging slots on weekly prostate cancer imaging workload. Br J Radiol. 2020 Jan 23:20190929.[Epub ahead of print]
de Bruijn R, Wimalasingham A, Szabados B, Stewart GD, Welsh SJ, Kuusk T, Blank C, Haanen J, Klatte T, Staehler M, Powles T, Bex A. Deferred Cytoreductive Nephrectomy Following Presurgical Vascular Endothelial Growth Factor Receptor-targeted Therapy in Patients with Primary Metastatic Clear Cell Renal Cell Carcinoma: A Pooled Analysis of Prospective Trial Data. Eur Urol Oncol. 2020 Jan 16. pii: S2588-9311(20)30001-8. [Epub ahead of print]
Manara A, Shemie SD, Large S, Healey A, Baker A, Badiwala M, Berman M, Butler AJ, Chaudhury P, Dark J, Forsythe J, Freed DH, Gardiner D, Harvey D, Hornby L1, MacLean J, Messer S, Oniscu GC, Simpson C, Teitelbaum J, Torrance S, Wilson LC, Watson CJE. Maintaining the permanence principle for death during in situ normothermic regional perfusion for donation after circulatory death organ recovery: A United Kingdom and Canada proposal. Am J Transplant. 2020 Jan 10. [Epub ahead of print]
Bryant RJ, Oxley J, Young GJ, Lane JA, Metcalfe C, Davis M, Turner EL, Martin RM, Goepel JR, Varma M, Griffiths DF, Grigor K, Mayer N, Warren AY, Bhattarai S, Dormer J, Mason M, Staffurth J, Walsh E, Rosario DJ, F Catto JW, Neal DE, Donovan L, Hamdy FC; ProtecT Study Group, Bollina P, Doble A, Doherty A, Gillatt D, Gnanapragasam V, Hughes O, Kockelbergh R, Kynaston H, Paul A, Paez E, Rowe E. The ProtecT trial: analysis of the patient cohort, baseline risk stratification and disease progression. BJU Int. 2020 Jan 3.
Books and Chapters
Iyer K and Khan WS. (eds) (2020) Orthopedics of the Upper and Lower Limb. Springer, Cham.
Davies BM and Khan WS (2020) Stem Cell Therapy in Orthopedics. In: Iyer K., Khan W. (eds) Orthopedics of the Upper and Lower Limb. Springer, Cham. pp 565-572
