2019
Lok LSC1,2, Dennison TW1, Mahbubani KM3, Saeb-Parsy K3,4, Chilvers ER5,6, Clatworthy MR. Phenotypically distinct neutrophils patrol uninfected human and mouse lymph nodes. Proc Natl Acad Sci USA. 2019 Sep 4. pii: 201905054. [Epub ahead of print]
Wu DA, Robb ML, Forsythe JLR, Bradley C, Cairns J, Draper H, Dudley C, Johnson RJ, Metcalfe W, Ravanan R, Roderick P, Tomson CRV, Watson CJE, Bradley JA, Oniscu GC. Recipient Comorbidity and Survival Outcomes after Kidney Transplantation: a UK-wide Prospective Cohort Study. Transplantation. 2019 Aug 19. [Epub ahead of print]
Kramer CSM, Franke-van Dijk MEI, Priddey AJ, Pongrácz T, Gnudi E, Car H, Karahan GE, van Beelen E, Zilvold-van den Oever CCC, Rademaker HJ, de Haan N, Wuhrer M, Kosmoliaptsis V, Parren PWH, Mulder A, Roelen DL, Claas FHJ, Heidt S. Recombinant human monoclonal HLA antibodies of different IgG subclasses recognising the same epitope: Excellent tools to study differential effects of donor-specific antibodies. HLA. 2019 Aug 12. doi: 10.1111/tan.13664. [Epub ahead of print]
Summers DM, Ahmad N, Randle LV, O’Sullivan AM, Johnson RJ, Collett DP, Attia M, Clancy M, Tavakoli A, Akyol M, Jamieson NV, Bradley JA, Watson CJE. Transplantation. 2019, Aug 8; [Online]
Li B, Cairns JA, Johnson RJ, Watson CJE, Roderick P, Oniscu GC, Metcalfe W, Bradley JA, Tomson CR, Draper H, Forsythe JL, Dudley C, Ravanan R. Equity-efficiency trade-offs associated with alternative approaches to deceased donor kidney allocation: a patient-level simulation. Transplantation. 2019, Aug 8; [Online]
Berdichevskia A, Birch MA, Markaki AE. Collagen scaffolds with tailored pore geometry for building three-dimensional vascular networks. Materials Letters. 2019 Aug 1; Vol. 248: 93-96
Richards J, Hossain M, Summers D, Slater M, Bartlett M, Kosmoliaptsis V, Wilson EC, Lagaac R, Sidders A, Foley C, Laing E, Hopkins V, Fitzpatrick-Creamer C, Hudson C, Thomas H, Turner S, Tambyraja A, Somalanka S, Hunter J, Dutta S, Lawman S, Salter T, Aslam M, Bagul A, Sivaprakasam R, Smith G, Moinuddin Z, Knight S, Gibbs P, Motallebzadeh R, Barnett N, Pettigrew G; SONAR trial group. Surveillance arterioveNous fistulAs using ultRasound (SONAR) trial in haemodialysis patients: a study protocol for a multicentre observational study. BMJ Open. 2019 Jul 23;9(7):e031210.
Georgiades F, Kosmoliaptsis V, Nicholson ML, Russell NK. Preventing conversion to open surgery during laparoscopic donor nephrectomy complicated by bleeding from the aorta. Clin Transplant. 2019 Jul 22:e13653 [Epub ahead of print]
Barrett T, Slough R, Sushentsev N, Shaida N, Koo BC, Caglic I, Kozlov V, Warren AY, Thankappannair V, Pinnock C, Shah N, Saeb-Parsy K, Gnanapragasam VJ, Sala E, Kastner C. Three-year experience of a dedicated prostate mpMRI pre-biopsy programme and effect on timed cancer diagnostic pathways. Clin Radiol. 2019 Jul 6. pii: S0009-9260(19)30279-X. [Epub ahead of print]
Johnson-Lynn SE, McCaskie AW, Coll AP, Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone Joint Res. 2018 Jun 5;7(5):373-378. eCollection 2018 May.
Richards J, Hossain M, Summers D, Slater M, Bartlett M, Kosmoliaptsis V, Wilson ECF, Lagaac R, Sidders A, Foley C, Laing E, Hopkins V, Fitzpatrick-Creamer C, Hudson C, Thomas H, Turner S, Tambyraja A, Somalanka S, Hunter J, Dutta S, Lawman S, Salter T, 10, Aslam M, Bagul A, Sivaprakasam R, Smith G, Moinuddin Z, Knight S, Gibbs P, Motallebzadeh R, Barnett N, Pettigrew. On behalf of the SONAR trial group. Surveillance Of arterioveNous fistulAe using ultRasound (SONAR) trial in haemodialysis patients: a study protocol for the multicentre observational study. BMJ Open 2019 Jul;0:e031210.
Vieira Braga FA, Kar G, Berg M, Carpaij OA, Polanski K, Simon LM, Brouwer S, Gomes T, Hesse L, Jiang J, Fasouli ES, Efremova M, Vento-Tormo R, Talavera-López C, Jonker MR, Affleck K, Palit S, Strzelecka PM, Firth HV, Mahbubani KT, Cvejic A, Meyer KB, Saeb-Parsy K, Luinge M, Brandsma CA, Timens W, Angelidis I, Strunz M, Koppelman GH, van Oosterhout AJ, Schiller HB, Theis FJ, van den Berge M, Nawijn MC, Teichmann SA. A cellular census of human lungs identifies novel cell states in health and in asthma. Nat Med. 2019 Jun 17.[Epub ahead of print]
Ceresa CDL, Nasralla D, Watson CJE, Butler AJ, Coussios CC, Crick K, Hodson L, Imber C, Jassem W, Knight SR, Mergental H, Ploeg RJ, Pollok JM, Quaglia A, Shapiro AMJ, Weissenbacher A, Friend PJ. Transient cold storage prior to normothermic liver perfusion may facilitate adoption of a novel technology. Liver Transpl. Jun 17.[Epub ahead of print]
Hsu RCJ, Barclay M, Loughran MA, Lyratzopoulos G, Gnanapragasam VJ, Armitage JN. Impact of Hospital Nephrectomy Volume on Intermediate to Long-term Survival in Renal Cell Carcinoma. BJU Int. Jun 17.[Epub ahead of print]
Tysoe OC, Justin AW, Brevini T, Chen SE, Mahbubani KT, Frank AK, Zedira H, Melum E, Saeb-Parsy K, Markaki AE, Vallier L, Sampaziotis F. Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue. Nat Protoc. 2019 Jun;14(6):1884-1925.
Johnson-Lynn SE, McCaskie AW, Coll AP, Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone Joint Res. 2018 Jun 5;7(5):373-378. eCollection 2018 May.
Rossi SH, Blick C, Nathan P, Nicol D, Stewart GD, Wilson ECF. Expert Elicitation to Inform a Cost-Effectiveness Analysis of Screening for Renal Cancer. Value in Health. 2019 May 31 [Epub ahead of print]
Hui Jin Ng N, Binte Jasmen J, Siang Lim C, Hui Lau H, Gomathi Krishnan V, Kadiwala J, Kulkarn RN, Ræder H, Vallier L, Hoon S, Kee Keong Teo A. HNF4A haploinsufficiency in MODY1 abrogates liver and pancreas differentiation from patient-derived iPSCs. iScience. 2019 May 27; epub
Gnanapragasam VJ, Barrett T, Thankapannair V, Thurtle D, Rubio-Briones J, Domínguez-Escrig J, Bratt O, Statin P, Muir K, Lophatananon A. Using prognosis to guide inclusion criteria, define standardized end‐points and stratify follow up in active surveillance for prostate cancer. BJU Int. 2019 May 7 [Epub ahead of print]
Gnanapragasam VJ, Barrett T, Massie C, Pacey S, Warren A. Using prognosis to guide early detection and treatment selection in non-metastatic prostate cancer. BJU Int. 2019 Apr;123(4):562-563.
Teresa Brevini, Walid Al-Akkad, Alessandro F Pellegata, Olivia C Tysoe, Luca Frenguelli, Si Emma Chen, Paolo De Coppi, Massimo Pinzani, Kourosh Saeb-Parsy, Ludovic Vallier, Giuseppe Mazza, Fotios Sampaziotis. PS-166-Repopulation of decellularized porcine bile ducts with human cholangiocyte organoids for the generation of human-sized bioengineered biliary tissue. Journal of Hepatology April 2019 Volume 70, Issue 1, Supplement, Pages e103–e104.
Taylor DM, Bradley JA, Bradley C, Draper H, Dudley C, Fogarty D, Fraser S, Johnson R, Leydon GM, Metcalfe W, Oniscu GC, Robb M, Tomson C, Watson CJE, Ravanan R, Roderick P; ATTOM investigators. Limited health literacy is associated with reduced access to kidney transplantation.Kidney Int. 2019 Mar 27. pii: S0085-2538(19)30049-3 [Epub ahead of print]
Klatte T, Stewart GD. Disagreement in risk groups for metastatic renal cancer. Nat Rev Urol. 2019 Mar 25. doi: 10.1038/s41585-019-0174-6. [Epub ahead of print]
Dabestani S, Beisland C, Stewart GD, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandéz-Pello S, Monagas S, Williams SP, Powles T, Van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Increased use of cross-sectional imaging for follow-up does not improve post-recurrence survival of surgically treated initially localized R.C.C.: results from a European multicenter database (R.E.C.U.R.). Scand J Urol. 2019 Mar 25:1-7.
Rossi SH, Fielding A, Blick C, Handforth C, Brown JE, Stewart GD. Setting Research Priorities in Partnership with Patients to Provide Patient-centred Urological Cancer Care. Eur Urol. 2019 Mar 22. pii: S0302-2838(19)30194-0. [Epub ahead of print]
Devoy B, Yaghmour KM, Chisari E, McDonnell SM, Khan W. Perioperative management of renal transplant patients undergoing total joint arthroplasty. J Perioper Pract. 2019, Mar 19:1750458919835435
Thurtle DR, Greenberg DC, Lee LS, Huang HH, Pharoah PD, Gnanapragasam VJ. Individual prognosis at diagnosis in nonmetastatic prostate cancer: Development and external validation of the PREDICT Prostate multivariable model. PLoS Med 2019 Mar 12;16(3).
Syafruddin SE, Rodrigues P, Vojtasova E, Patel SA, Zaini MN, Burge J, Warren AY, Stewart GD, Eisen T, Bihary D, Samarajiwa SA, Vanharanta S. A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma. Nat Commun. 2019 Mar 11;10(1):1152.
Qureshi MS, Alsughayyir J, Chhabra M, Ali JM, Goddard MJ, Devine CA, Conlon TM, Linterman MA, Motallebzadeh R, Pettigrew GJ. Germinal center humoral autoimmunity independently mediates progression of allograft vasculopathy. J Autoimmun. 2019 Mar;98:44-58
Van Hemelrijck M, Ji X, Helleman J, Roobol MJ, van der Linden W, Nieboer D, Bangma CH, Frydenberg M, Rannikko A, Lee LS, Gnanapragasam VJ, Kattan MW; Members of the Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance GAP3 consortium; Members of the Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance GAP3 consortium. Reasons for Discontinuing Active Surveillance: Assessment of 21 Centres in 12 Countries in the Movember GAP3 Consortium. Eur Urol. 2019 Mar;75(3):523-531.
Castro-Dopico T, Dennison TW, Ferdinand JR, Mathews RJ, Fleming A, Clift D, Stewart BJ, Jing C, Strongili K, Labzin LI, Monk EJM, Saeb-Parsy K, Bryant CE, Clare S, Parkes M, Clatworthy MR. Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis. Immunity. 2019 Feb 27. [Epub ahead of print]
Rossi SH, Blick C, Handforth C, Brown JE, Stewart GD; Renal Cancer Gap Analysis Collaborative. Essential Research Priorities in Renal Cancer: A Modified Delphi Consensus Statement. Eur Urol Focus. 2019 Feb 13. [Epub ahead of print]
Merriel SWD, Hetherington L, Seggie A, Castle JT, Cross W, Roobol MJ, Gnanapragasam V, Moore CM. Best practice in Active Surveillance for men with prostate cancer: A Prostate Cancer UK consensus statement. Prostate Cancer UK Expert Reference Group on Active Surveillance. BJU Int. 2019 Feb 11 [Epub ahead of print]
Palmer AJR, Ayyar Gupta V, Fernquest S, Rombach I, Dutton SJ, Mansour R, Wood S, Khanduja V, Pollard TCB, McCaskie AW, Barker KL, Andrade TJMD, Carr AJ, Beard DJ, Glyn-Jones S; FAIT Study Group. Arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of symptomatic femoroacetabular impingement: multicentre randomised controlled trial. BMJ. 2019, Feb 7;364:l185.
Ranmuthu CDS, Ranmuthu CKI, Russell JC, Singhania D, Khan WS. Are the Biological and Biomechanical Properties of Meniscal Scaffolds Reflected in Clinical Practice? A Systematic Review of the Literature. Int J Mol Sci. 2019, Feb 1;20(3).
Smith SF, Miakhil SI, Lockett C. An unusual cause of testicular pain: single organ lymphocytic vasculitis. Journal of Clinical Urology. 2019, Feb. Epub.
Yaghmour KM, Chisari E, Khan WS. Single-Stage Revision Surgery in Infected Total Knee Arthroplasty: A PRISMA Systematic Review. J Clin Med. 2019, Feb 2;8(2).
Summers DM, Pettigrew GJ. Uncontrolled DCD donation-tilting at windmills or pushing against an open door? Kidney Int. 2019 Feb;95(2):263-265.
Chhabra M, Alsughayyir J, Qureshi MS, Mallik M, Ali JM, Gamper I, Moseley EL, Peacock S, Kosmoliaptsis V, Goddard MJ, Linterman MA, Motallebzadeh R, Pettigrew GJ. Germinal Center Alloantibody Responses Mediate Progression of Chronic Allograft Injury. Front Immunol. 2019 Jan 23;9:3038.
Thompson ER, Irwin EA, Trotter P, Ibrahim IK, Tingle SJ, White SA, Manas DM, Wilson CH. UK registry analysis of donor substance misuse and outcomes following pancreas transplantation. Clin Transplant. 2019 Jan 19:e13481.
Alsughayyir A, Chhabra M, Qureshi MS, Mallik M, Ali JM, Gamper I, Moseley EL, Peacock S, Kosmoliaptsis K, Goddard MJ, Linterman MA, Motallebzadeh R and Pettigrew GJ. Relative Frequencies of Alloantigen-Specific Helper CD4 T Cells and B Cells Determine Mode of Antibody-Mediated Allograft Rejection. Front Immunol. 2019 Jan; 9 article 3039.
Taylor R, Allen E, Richards JA, Goh AM, Neuberger J, Collett D, Pettigrew GJ On behalf of members of the Liver Advisory Group to NHS Blood Transplant. Survival advantage for patients accepting the offer of a circulatory death liver transplant. Journal of Hepatology. 2019 Jan. Epub
Tsekes D, Konstantopoulos G, Khan WS, Rossouw D, Elvey M, Singh J. Use of stem cells and growth factors in rotator cuff tendon repair. Eur J Orthop Surg Traumatol. 2019 Jan 9. [Epub ahead of print]
Smith SF, Hosgood SA, Nicholson ML. Ischemia-reperfusion injury in renal transplantation: 3 key signaling pathways in tubular epithelial cells. Kidney Int. 2019 Jan;95(1):50-56. Review.
2018
Qureshi MS, Alsughayyir J, Chhabra M, Ali JM, Goddard MJ, Devine C, Conlon TM, Linterman MA, Motallebzadeh R, Pettigrew GJ. Data regarding transplant induced germinal center humoral autoimmunity. Data Brief. 2018 Dec 28;22:647-657
Watson CJE, Hunt F, Messer S, Currie I, Large S, Sutherland A, Crick K, Wigmore SJ, Fear C, Cornateanu S, Randle LV, Terrace JD, Upponi S, Taylor R, Allen E, Butler AJ, Oniscu GC. In situ normothermic perfusion of livers in controlled circulatory death donation may prevent ischemic cholangiopathy and improve graft survival. Am J Transplant. 2018 Dec 27. [Epub ahead of print]
Tanase CE, Golozar M, Best SM, Brooks RA. Cell response to plasma electrolytic oxidation surface-modified low-modulus β-type titanium alloys. Colloids Surf B Biointerfaces. 2018 Dec 26;176:176-184. [Epub ahead of print]
Dolezalova N, Gruszczyk A, Mahbubani KTA, Casey J, Slater NKH, Saeb-Parsy K. Characterising diffusion kinetics to improve pancreatic islet cryopreservation. Cryobiology. Volume 85, December 2018, Pages 144-145
Gnanapragasam V, Barrett T, Massie C, Pacey S, Warren A. Using prognosis to guide early detection and treatment selection in non-metastatic prostate cancer. BJU International. 2018 Nov 30. [Epub ahead of print]
Stacey G, Andrews P, Asante C, Barbaric I, Barry J, Bisset L, Braybrook J, Buckle R, Chandra A, Coffey P, Crouch S, Driver P, Evans A, Gardner J, Ginty P, Goldring C, Hay DC, Healy L, Hows A, Hutchinson C, Jesson H, Kalber T, Kimber S, Leathers R, Moyle S, Murray T, Neale M, Pan D, Park BK, Rebolledo RE, Rees I, Rivolta MN, Ritchie A, Roos EJ, Saeb-Parsy K, Schröder B, Sebastien S, Thomas A, Thomas RJ, Turner M, Vallier L, Vitillo L, Webster A, Williams D. Science-based assessment of source materials for cell-based medicines: report of a stakeholders workshop. Regen Med. 2018 Nov 29. [Epub ahead of print]
Mylonas KJ, Anderson J, Sheldrake TA, Hesketh EE, Richards JA, Ferenbach DA, Kluth DC, Savill J, Hughes J. Granulocyte macrophage-colony stimulating factor: A key modulator of renal mononuclear phagocyte plasticity. Immunology. 2018 Nov 9 Epub
Siu JHY, Surendrakumar V, Richards JA, Pettigrew GJ. T cell Allorecognition Pathways in Solid Organ Transplantation. Frontiers in Immunology. 2018 Nov Epub.
Martincorena I, Fowler JC, Wabik A, Lawson ARJ, Abascal F, Hall MWJ, Cagan A, Murai K, Mahbubani K, Stratton MR, Fitzgerald RC, Handford PA, Campbell PJ, Saeb-Parsy K, Jones PH. Somatic mutant clones colonize the human esophagus with age. Science. 2018 Nov 23;362(6417):911-917. Epub 2018 Oct 18.
Beisland C, Dabestani S, Stewart G, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandéz-Pello S, Monagas S, Williams SP, Torbrand C, Powles T, Van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Making a judgement on the potential curability of recurrent Renal Cell Carcinoma (RCC): Differences in global per protocol vs. investigator based assessment. European Urology Supplements. 2018 Nov 17(14) e3025–e3026.
Mallon DH, Kling C, Robb M, Ellinghaus E, Bradley JA, Taylor CJ, Kabelitz D, Kosmoliaptsis V. Predicting Humoral Alloimmunity from Differences in Donor and Recipient HLA Surface Electrostatic Potential. Journal of Immunology. 2018 Nov 14 pii: ji1800683. [Epub ahead of print]
Mouliere F, Chandrananda D, Piskorz AM, Moore EK, Morris J, Ahlborn LB, Mair R, Goranova T, Marass F, Heider K, Wan JCM1, Supernat A, Hudecova I, Gounaris I, Ros S, Jimenez-Linan M, Garcia-Corbacho J, Patel K, Østrup O, Murphy S, Eldridge MD, Gale D, Stewart GD, Burge J, Cooper WN, van der Heijden MS, Massie CE, Watts C, Corrie P, Pacey S, Brindle KM, Baird RD, Mau-Sørensen M, Parkinson CA, Smith CG, Brenton JD, Rosenfeld N. Enhanced detection of circulating tumor DNA by fragment size analysis. Science Translational Medicine. 2018 Nov 7;10(466). pii: eaat4921.
Serrano F, Bernard WG, Granata A, Iyer D, Steventon B, Kim M, Vallier L, Gambardella L, Sinha S. A novel human pluripotent stem cell-derived neural crest model of Treacher Collins Syndrome shows defects in cell death and migration. Stem Cells and Development. 2018 Oct 30. [Epub ahead of print]
Grandy R, Tomaz R, Vallier L. Modeling Disease with Inducible Pluripotent Stem Cells. Annual Review of Pathology. 2018 Oct 24. [Epub ahead of print]
Nicholson ML, Yong C, Trotter PB, Grant L, Hosgood SA. Risk factors for transplant renal artery stenosis after live donor transplantation. British Journal of Surgery. 2018 Oct 22. [Epub ahead of print]
DiRito JR, Hosgood SA, Tietjen GT, Nicholson ML. The future of marginal kidney repair in the context of normothermic machine perfusion. Am J Transplant. 2018 Oct;18(10):2400-2408
Rashidi H, Luu NT, Alwahsh SM, Ginai M, Alhaque S, Dong H, Tomaz RA, Vernay B, Vigneswara V, Hallett JM, Chandrashekran A, Dhawan A, Vallier L, Bradley M, Callanan A, Forbes SJ, Newsome PN, Hay DC. 3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo. Archives of Toxicology. 2018 Oct;92(10):3117-3129.
Van Hemelrijck M, Ji X2, Helleman J, Roobol MJ, van der Linden W, Nieboer D, Bangma CH, Frydenberg M, Rannikko A, Lee LS, Gnanapragasam VJ, Kattan MW. Reasons for Discontinuing Active Surveillance: Assessment of 21 Centres in 12 Countries in the Movember GAP3 Consortium. European Urology. 2018 Oct 29. pii: S0302-2838(18)30813-3. [Epub ahead of print]
Hsu RCJ, Barclay M, Loughran MA, Lyratzopoulos G, Gnanapragasam VJ, Armitage JN. Time trends in service provision and survival outcomes for patients with renal cancer treated by nephrectomy in England 2000-2010. BJU International. 2018 Oct;122(4):599-609.
Dabestani S, Beisland C, Stewart GD, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandéz-Pello S, Monagas S, Williams SP, Torbrand C, Powles T, Van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Intensive Imaging-based Follow-up of Surgically Treated Localised Renal Cell Carcinoma Does Not Improve Post-recurrence Survival: Results from a European Multicentre Database (RECUR). European Urology. 2018 Oct 11. pii: S0302-2838(18)30748-6.[Epub ahead of print]
Lloyd T, Patruno G, Macchi A, Czarniecki M, Gnanapragasam V, Koo B, Saeb-Parsy K, Nadeem S, Warren A, Bratt O, Shah N, Barrett T, Kastner C. “Saturation target biopsies” – can a reduction in biopsy cores maintain accuracy of mpMRI supported target and systematic trans-perineal prostate biopsies? European Urology Supplements. 2018 Sept, Vol. 17, Issue 8, p313
Mongelli L, Patruno G, Blumenthal Y, Warren A, Koo B, Gnanapragasam V, Saeb-Parsy K, Barrett T, Kastner C. The impact of prostate MRI-based transperineal biopsies (M-TPBx) on an Active Surveillance (ActS) practice in a tertiary referral centre. European Urology Supplements. 2018 Sept, Vol. 17, Issue 8, p220
Usman A, Yuan J, Patterson AJ, Graves MJ, Varty K, Sadat U, Gillard JH, Neovascularization in Vertebral Artery Atheroma-A Dynamic Contrast-Enhanced Magnetic Resonance Imaging-Based Comparative Study in Patients with Symptomatic and Asymptomatic Carotid Artery Disease. J Stroke Cerebrovasc Dis. 2018 Sep;27(9):2505-2512
Klatte T, Stewart GD. Renal cell carcinoma: standards and controversies. World Journal Urology. 2018 Sep 12 [Epub ahead of print]
Ranmuthu CDS, Ranmuthu CKI, Khan WS. Evaluating the Current Literature on Treatments Containing Adipose-Derived Stem Cells for Osteoarthritis: a Progress Update. Current Rheumatology Reports. 2018 10;20(11):67 Review
Tarkin JM, Le EPV, Calcagno C, Dweck MR,Evans NR, Chowdhury MM, Newby DE, Fayad ZA, Bennett MR, Rudd JHF. 68Ga-DOTATATE PET identifies myocardial inflammation and bone marrow monocyte mobilisation after myocardial infarction. Cardiovascular Research. 2018 Sep 114(suppl_2):S9-S10
Woods S, Barter MJ, Elliott HR, McGillivray CM, Birch MA, Clark IM, Young DA. miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse. Matrix Biology. 2018 Sep 5. [Epub ahead of print]
Sadat U, Mariam NBG, Usman A, Chowdhury MM, El Nakhai E, DaCosta, OF, Gillard JH, Hayes PD, Varty K. Association Between Abdominal Visceral Artery Calcification and All-Cause Mortality-A Computerized Tomography Imaging-Based Longitudinal Follow-Up Study. Angiology. 2018 Sep 4 [Epub ahead of print]
Tcacencu I, Rodrigues N, Alharbi N, Benning M, Toumpaniari S, Mancuso E, Marshall M, Bretcanu O, Birch MA, McCaskie AW and Dalgarno KW. Osseointegration of porous apatite-wollastonite and poly (lactic acid) composite structures created using 3D printing techniques. Materials Science and Engineering: C. 2018 Aug 90, 1-7
Frith TJ, Granata I, Wind M, Stout E, Thompson O, Neumann K, Stavish D, Heath PR, Ortmann D, Hackland JO, Anastassiadis K, Gouti M, Briscoe J, Wilson V, Johnson SL, Placzek M, Guarracino MR, Andrews PW, Tsakiridis A. Human axial progenitors generate trunk neural crest cells in vitro. eLife. 2018 Aug 10;7. pii: e35786.
Duan P, Toumpaniari R, Partridge S, Birch MA, Genever PA, Bull SJ, Dalgarno KW, McCaskie AW and Chen J. How cell culture conditions affect the microstructure and nanomechanical properties of extracellular matrix formed by immortalized human mesenchymal stem cells: An experimental and modelling study. Materials Science and Engineering: C. 2018 Aug 89, 149-159
Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S. Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors. Science. 2018 Aug 10;361(6402):594-599.
Steinberg J, Brooks RA, Southam L, Bhatnagar S, Roumeliotis TI, Hatzikotoulas K, Zengini E, Wilkinson JM, Choudhary JS, McCaskie AW and Zeggini E. Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology (Oxford) 2018 Aug 1;57(8):1481-1489
Wiebe C, Kosmoliaptsis V, Pochinco D, Taylor C, Nickerson PA. Comparison of HLA Molecular Mismatch Methods to Determine HLA Immunogenicity. Transplantation. Aug;102(8):1338-1343.
Mitchell TJ, Rossi SH, Klatte T, Stewart GD. Genomics and clinical correlates of renal cell carcinoma World Journal of Urology. 2018 Aug 11. [Epub ahead of print]
Marconi L, de Bruijn R, van Werkhoven E, Beisland C, Fife K, Heidenreich A, Kapoor A, Karam J, Kauffmann C, Klatte T, Ljungberg B, Matin S, Sjoberg D, Staehler M, Stewart GD, Tanguay S, Uzzo R, Welsh S, Wood L, Wood C, Bex A. External validation of a predictive model of survival after cytoreductive nephrectomy for metastatic renal cell carcinoma. World Journal of Urology. 2018 Aug 1 [Epub ahead of print]
Copley HC, Elango M, Kosmoliaptsis V. Assessment of human leukocyte antigen immunogenicity: current methods, challenges and opportunities. Current Opinion in Organ Transplant. 2018 Aug;23(4):477-485.
Archer DE, Mafi R, Mafi P, Khan W. Preclinical Studies on Biomaterial Scaffold use in Knee Ligament Regeneration: A systematic review. Current Stem Cell Research & Therapy. 2018;13(8):691-701
DiRito JR, Hosgood SA, Tietjen GT, Nicholson ML. The future of marginal kidney repair in the context of normothermic machine perfusion. Am J Transplant. 2018 Oct;18(10):2400-2408. Epub 2018 Jul 2. Review.
Rodrigues P, Patel SA, Harewood L, Olan I, Vojtasova E, Syafruddin SE, Zaini MN, Richardson EK, Burge J, Warren AY, Stewart GD, Saeb-Parsy K, Samarajiwa SA, Vanharanta S. NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis. Cancer Discovery. 2018 Jul;8(7):850-865.
Arshad Z, Pettitt DA, Chadha P, Davies B, Carr A, Walmsley P. Artificial Intelligence to Predict Periprosthetic Joint Infection after Total Hip Replacement. International Journal of Surgery. 2018 July; 55:S8
Thurtle D, Barrett T, Thankappan-Nair V, Koo B, Warren A, Kastner C, Saeb-Parsy K, Kimberley-Duffell J, Gnanapragasam VJ. Progression and treatment rates using an active surveillance protocol incorporating image-guided baseline biopsies and multiparametric magnetic resonance imaging monitoring for men with favourable-risk prostate cancer. BJU International. 2018 Jul;122(1):59-65.
Hurrell T, Segeritz CP, Vallier L, Lilley KS, Cromarty AD. Proteomic Comparison of Various Hepatic Cell Cultures for Preclinical Safety Pharmacology. Toxicological Science. 2018 Jul 1;164(1):229-239.
Banham GD, Flint SM, Torpey N, Lyons PA, Shanahan DN, Gibson A, Watson CJE, O’Sullivan AM, Chadwick JA, Foster KE, Jones RB, Devey LR, Richards A, Erwig LP, Savage CO, Smith KGC, Henderson RB, Clatworthy MR. Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial. Lancet. 2018 Jun 14. pii: S0140-6736(18)30984-X. Epub 2018 Jun 14
Thurtle D, Gordon E, Brierly R, Conway CJ, McLoughlin J. GP perception of prostate-specific antigen testing has improved, but more awareness of prostate cancer risk in younger patients is still awaited. Prostate international. 2018 Jun;6(2):61-65.
Johnson-Lynn SE, McCaskie AW, Coll AP and Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone and Joint Research. 2018 Jun 5;7(5):373-378
Segeritz CP, Rashid ST, Cardoso de Brito M, Paola MS, Ordonez A, Morell CM, Kaserman JE, Madrigal P, Hannan N, Gatto L, Tan L, Wilson AA, Lilley K, Marciniak SJ, Gooptu B, Lomas DA, Vallier L. hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency. Journal of Hepatology. 2018 Jun 4. pii: S0168-8278(18)32113-5.
Martin JL, Gruszczyk AV, Beach TE, Murphy MP, Saeb-Parsy K. Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury. Pediatric Nephrology. 2018 Jun 2. [Epub ahead of print]
Chowdhury MM, Rudd JHF, Coughlin PA. Response to “Re. Abdominal Aortic Aneurysm Calcification: Are Biochemical Markers a Missing Piece of the Puzzle?” European Journal of Vascular and Endovascular Surgery. 2018 Jun;55(6):900-901
Oniscu GC, Watson CJE, Wigmore SJ. Redefining futility in DCD liver transplantation in the era of novel perfusion technologies. Journal of Hepatology. 2018 Jun;68(6):1327-1328.
Kwon K-A, Juhasz JA, Brooks RA. Best SM. Bioactive conformable hydrogel-carbonated hydroxyapatite nanocomposite coatings on Ti-6Al-4V substrates. Materials Technology 2018 June [published online]
Ardakani AHG, Khan WS. The role of ageing and gender in musculoskeletal stem cell. Current Stem Cell Research & Therapy, 2018 13(6):432-437
Thurtle D, Starling L, Leonard K, Stone T, Gnanapragasam VJ. Improving the safety and tolerability of local anaesthetic outpatient transperineal prostate biopsies: A pilot study of the CAMbridge PROstate Biopsy (CAMPROBE) method. Journal of Clinical Urology. 2018 May;11(3):192-199.
Nasralla D, Coussios CC, Mergental H, Akhtar MZ, Butler AJ, Ceresa CDL, Chiocchia V, Dutton SJ, García-Valdecasas JC, Heaton N, Imber C, Jassem W, Jochmans I, Karani J, Knight SR, Kocabayoglu P, Malagò M, Mirza D, Morris PJ, Pallan A, Paul A, Pavel M, Perera MTPR, Pirenne J, Ravikumar R, Russell L, Upponi S, Watson CJE, Weissenbacher A, Ploeg RJ, Friend PJ; Consortium for Organ Preservation in Europe. A randomized trial of normothermic preservation in liver transplantation. Nature. 2018 May;557(7703):50-56.
MacKay JW, Kapoor G, Driban JB, Lo GH, McAlindon TE, Toms AP, McCaskie AW and Gilbert FJ. Association of subchondral bone texture on magnetic resonance imaging with radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative Bone Ancillary Study. European Radiology. 2018 May 2. [Epub ahead of print]
Gill EL, Li X, Birch MA, Huang YYS. Multi-length scale bioprinting towards simulating microenvironmental cues. Biodes Manuf. 2018, May 1(2):77-88. [Epub]
Hodgson B, Mafi R, Mafi P, Khan WS. The Regulation of Differentiation of Mesenchymal Stem-cells into Skeletal Muscle: A Look at Signalling Molecules Involved in Myogenesis. Current stem cell research & therapy 2018 13(5), 384-407
Khan H, Mafi P, Mafi R, Khan W. The effects of ageing on differentiation and characterisation of human mesenchymal stem cells. Current stem cell research & therapy 2018 13(5), 378-383
Zengini E, Hatzikotoulas K, Tachmazidou I, Steinberg J, Hartwig FP, Southam L, Hackinger S, Boer CG, Styrkarsdottir U, Gilly A, Suveges D, Killian B, Ingvarsson T, Jonsson H, Babis GC, McCaskie A, Uitterlinden AG, van Meurs JBJ, Thorsteinsdottir U, Stefansson K, Davey Smith G, Wilkinson JM, Zeggini E. Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. Nature Genetics. 2018 Apr;50(4):549-558.
Baird A, Lindsay T, Everett A, Iyemere V, Paterson YZ, McClellan A, Henson FMD and Guest DJ. Osteoblast differentiation of equine induced pluripotent stem cells. Biology Open: 2018 7(5)bio.033514
Mitchell TJ, Turajlic S, Rowan A, Nicol D, Farmery JHR, O’Brien T, Martincorena I, Tarpey P, Angelopoulos N, Yates LR, Butler AP, Raine K, Stewart GD, Challacombe B, Fernando A, Lopez JI, Hazell S, Chandra A, Chowdhury S, Rudman S, Soultati A, Stamp G, Fotiadis N, Pickering L, Au L, Spain L, Lynch J, Stares M, Teague J, Maura F, Wedge DC, Horswell S, Chambers T, Litchfield K, Xu H, Stewart A, Elaidi R, Oudard S, McGranahan N, Csabai I, Gore M, Futreal PA, Larkin J, Lynch AG, Szallasi Z, Swanton C, Campbell PJ; TRACERx Renal Consortium. Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal. Cell. 2018 Apr 19;173(3):611-623.e17.
Yiangou L, Ross ADB, Goh KJ, Vallier L. Human Pluripotent Stem Cell-Derived Endoderm for Modeling Development and Clinical Applications. Cell Stem Cell. 2018 Apr 5;22(4):485-499.
Xing Y, Zhao S, Wei Q, Gong S, Zhao X, Zhou F, Ai-Lamki R, Ortmann D, Du M, Pedersen R, Shang G, Si S, Morrell NW, Yang J. A novel piperidine identified by stem cell-based screening attenuates pulmonary arterial hypertension by regulating BMP2 and PTGS2 levels. European Respiratory Journal. 2018 Apr 4;51(4). pii: 1702229.
Kohlhauer M, Dawkins S, Costa ASH, Lee R, Young T, Pell VR, Choudhury RP, Banning AP, Kharbanda RK; Oxford Acute Myocardial Infarction (OxAMI) Study, Saeb-Parsy K, Murphy MP, Frezza C, Krieg T, Channon KM. Metabolomic Profiling in Acute ST-Segment-Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia-Reperfusion Injury. Journal of the American Heart Association. 2018 Apr 6;7(8). pii: e007546. doi: 10.1161/JAHA.117.007546.
Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D’Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A. Report of the Key Opinion Leaders Meeting on Stem Cell-Derived Beta Cells.Transplantation. 2018 Apr 30.
Trotter PB, Summers DM, Ushiro-Lumb I, Robb M, Bradley JA, Powell J, Watson CJE, Neuberger J. Use of Organs From Hepatitis C Virus-Positive Donors for Uninfected Recipients: A Potential Cost-Effective Approach to Save Lives? Transplantation. 2018 Apr;102(4):664-672.
Klatte T, Rossi SH, Stewart GD. Prognostic factors and prognostic models for renal cell carcinoma: a literature review. World Journal of Urology. 2018 Apr 30. [Epub ahead of print]
Rossi SH, Klatte T, Usher-Smith J, Stewart GD.(2018) Epidemiology and screening for renal cancer. World J Urol. 2018 Apr 2. [Epub ahead of print]
Hosgood SA, Moore T, Qurashi M, Adams T, Nicholson ML. Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. Artificial Organs. 2018 Apr 2. [Epub ahead of print]
Tonkin-Crine S, Pruthi R, Taylor DM, Leydon GM, Calestani M, Oniscu GC, Bradley JA, Tomson CR, Bradley C, Dudley C, Watson CJE, Draper H, Johnson RJ, Metcalfe W, Fogarty DG, Ravanan R, Roderick P. Assessing Consensus Between UK Renal Clinicians on Listing for Kidney Transplantation: A Modified Delphi Study. Transplant Direct. 2018 Apr 18;4(5):e343.
Khan WS. Outcomes of alveolar soft part sarcoma from a regional tumour unit. Acta Orthopaedica Belgica 2018 April [published online]
Khan S, Mafi P, Mafi R, Khan W. A Systematic Review of Mesenchymal Stem Cells in Spinal Cord Injury, Intervertebral Disc Repair and Spinal Fusion. Current stem cell research & therapy 2018 13(4), 316-323
Killington K, Mafi R, Mafi P, Khan WS. A systematic review of clinical studies investigating mesenchymal stem cells for fracture non-union and bone defects. Current stem cell research & therapy 2018 13(4), 284-291
MacKay JW, Low SBL, Smith TO, Toms AP, McCaskie AW. and Gilbert FJ. Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis. Osteoarthritis & Cartilage. 2018 Mar 14. pii: S1063-4584(18)31069-0.
Hosgood SA, Thompson E, Moore T, Wilson CH, Nicholson ML. Normothermic machine perfusion for the assessment and transplantation of declined human kidneys from donation after circulatory death donors. British Journal of Surgery. 2018 Mar;105(4):388-394.
Borakati A, Mafi R, Mafi P, Khan WS. A systematic review and meta-analysis of clinical trials of mesenchymal stem cell therapy for cartilage repair. Current stem cell research & therapy 2018 13(3), 215-225
Bertero A, Brown S, Madrigal P, Osnato A, Ortmann D, Yiangou L, Kadiwala J, Hubner NC, de Los Mozos IR, Sadée C, Lenaerts AS, Nakanoh S, Grandy R, Farnell E, Ule J, Stunnenberg HG, Mendjan S, Vallier L. The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency. Nature. 2018 Mar 8;555(7695):256-259.
Dabestani S, Beisland C, Stewart GD, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandéz-Pello S, Monagas S, Williams SP, Torbrand C, Powles T, Van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Long-term Outcomes of Follow-up for Initially Localised Clear Cell Renal Cell Carcinoma: RECUR Database Analysis. European Urolology Focus. 2018 Mar 7. [Epub ahead of print]
Watson CJE, Jochmans I. From “Gut Feeling” to Objectivity: Machine Preservation of the Liver as a Tool to Assess Organ Viability. Current Transplantation Reports. 2018 March;5(1):72-81.
O’Keeffe LM, Ramond A, Oliver-Williams C, Willeit P, Paige E, Trotter P, Evans J, Wadström J, Nicholson M, Collett D, Di Angelantonio E. Mid- and Long-Term Health Risks in Living Kidney Donors: A Systematic Review and Meta-analysis. Annals of Internal Medicine. 2018 Feb 20;168(4):276-284.
Watson CJE, Kosmoliaptsis V, Pley C, Randle L, Fear C, Crick K, Gimson AE, Allison M, Upponi S, Brais R, Jochmans I, Butler AJ. Observations on the ex situ perfusion of livers for transplantation. American Journal of Transplantation. 2018 Feb 8. [Epub ahead of print]
Lydon H, Brooks R, McCaskie A, Henson F. Peripheral mononuclear blood cell apheresis in a preclinical ovine model. BMC Veterinary Research. 2018 Feb 13;14(1):47.
Lawton JM, Habib M, Ma B, Brooks RA, Best SM, Lewis AL, Rushton N, Bonfield W. Correction to: The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo. Journal of Materials Science: Materials in Medicine. 2018 Feb 22;29(3):26
Bertero A, Yiangou L, Brown S, Ortmann D, Pawlowski M, Vallier L. Conditional Manipulation of Gene Function in Human Cells with Optimized Inducible shRNA. Current Protocols in Stem Cell Biology. 2018 Feb 28;44:5C.4.1-5C.4.48.
Briggs W, Guevel B, McCaskie AW and McDonnell SM. Multi- and univariate analyses of the weekend effect for elective lower-limb joint replacements. Annals of the Royal College of Surgeons England. 2018 Jan;100(1):42-46.
Hakeem A, Chen J, Iype S, Clatworthy M, Watson C, Godfrey EM, Upponi S, Saeb-Parsy K. Pancreatic Allograft Thrombosis: Suggestion for a CT grading system and management algorithm. American Journal of Transplantation 2018 18(1):163-179.
Books and Chapters
Williams N, O’Connell PR and McCaskie AW (Editors) (2018). Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
McCaskie AW and Bradley A (2018) Tissue Engineering and Regeneration Part 1: Basic Principles, ch.4, pp.33-41. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC PressWilliams N, O’Connell PR and McCaskie AW (Editors) (2018).
McDonnell SM and Pandit HG (2018) History taking and clinical examination in musculoskeletal disease. Part 5: Elective Orthopaedics, ch.31 pp.436-462. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Khanduja V and Khan W(2018) Hip and Knee Part 5: Elective Orthopaedics, ch.35 pp.511-523. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Seah MKT, Khan W (2018) Minimally Invasive Surgery of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.5 pp.73-85
Seah MKT, Khan W (2018) Computer-Assisted Navigation of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.6 pp.87-99
Previous years
