Lead: Mr Kourosh Saeb-Parsy, University Reader and Honorary Transplant Consultant
Cambridge Biorepository for Translational Medicine (CBTM)
The Cambridge Biorepository for Translational Medicine aims to provide UK researchers with unparalleled access to live normal cells and tissues from human donors.
It will support innovative basic and translational research that is otherwise impossible to conduct due to the current lack of access to live normal tissue. CBTM will support the full spectrum of research that is dependent on this rare resource, including in regenerative medicine, infection and immunity, cellular and molecular medicine, cancer, systems medicine, transplantation and others.
Comprehensive linked data management of diverse projects utilising live cells and tissue from the same organs and donors enables creation of considerable synergy and scientific value beyond the individual studies. CBTM was established by the Saeb-Parsy Group at the Department of Surgery and functions as a core facility accessible to all research groups on the Cambridge biomedical campus, as well as to external academic and commercial collaborators.
By providing reliable access to fresh tissue for its collaborators, CBTM promotes research that is ultimately anticipated to improve the quality of healthcare for patients.
Key Publications Supported by CBTM:
Martin et al. Nature Metabolism. 2019, in press.
Vieira Braga et al. Nature Medicine. 2019, 25(7):1153-1163
Tysoe et al. Nature Protocols. 2019, 14(6):1884-1925.
Martincorena et al. Science. 2018, 362(6417):911-917.
Broutier et al. Nature Medicine. 2017, 23(12):1424-1435.
Sampaziotis et al. Nature Medicine. 2017, 23(8):954-963
Cambridge In Vivo Assessment Platform (CIVAP)
The Cambridge In Vivo Assessment Platform aims to provide infrastructure, expertise and resources to accelerate pre-clinical translation of laboratory human research in a range of disciplines including regenerative medicine and cancer.
CIVAP was established by the Saeb-Parsy Group at the Department of Surgery and functions as a core facility accessible to all research groups on the Cambridge biomedical campus, as well as to external academic and commercial collaborators.
Its objective is to enable research groups to conduct high quality and pioneering in vivo studies rapidly, optimally and cost-effectively, with a particular emphasis on Replacement, Reduction and Refinements in experimental animal use.
Key Publications Supported by CIVAP:
Martin et al. Nature Metabolism. 2019, in press.
Tysoe et al. Nature Protocols. 2019, 14(6):1884-1925.
Rodrigues et al. Cancer Discovery. 2018, 8(7):850-865.
Ng et al. Biomaterials. 2018, 182:299-311.
Broutier et al. Nature Medicine. 2017, 23(12):1424-1435.
Sampaziotis et al. Nature Medicine. 2017, 23(8):954-963.
