Professor of Transplantation and Honorary Consultant Surgeon
Professor Watson is part of the Cambridge abdominal organ transplant unit performing liver, kidney, pancreas and intestinal transplants. His main interest lies in optimising the use of organs for transplantation. This has included work to quantify the risks of donor transmitted disease, particularly brain tumours, as well as work aimed to improve the function of organs post transplantation in particular those donated after circulatory death (DCD). This has included pioneering in situ normothermic regional perfusion of DCD donors in the UK and ex situ hypothermic perfusion of kidneys and normothermic perfusion of livers prior to transplantation. His previous work included some of the early studies of the immunosuppressants sirolimus and alemtuzumab
Watson CJE , Kosmoliaptsis V, Randle LV, Gimson AE, Brais R , Klinck JR, Hamed M, Tsyben A, Butler AJ (2017) Normothermic perfusion in the assessment and preservation of declined livers prior to transplantation: hyperoxia and vasoplegia – important lessons from the first 12 cases. Transplantation.
Butler AJ, Randle LV, Watson CJ (2014) Normothermic regional perfusion for donation after circulatory death without prior heparinization. Transplantation, 97 ; 1272-1278.
Watson CJE, Wells AC, Roberts RJ, Akoh JA, Friend PJ, Akyol M, Calder FR, Allen JE, Jones MN, Collett D, Bradley JA (2010) Cold machine perfusion versus static cold storage of kidneys donated after cardiac death: a UK multicenter randomized controlled trial. Am J Transplant, 10; 1991-1999.
Watson CJ, Roberts R, Wright KA, Greenberg DC, Rous BA, Brown CH, Counter C, Collett D, Bradley JA (2010) How safe is it to transplant organs from deceased donors with primary intracranial malignancy? An analysis of UK Registry data. Am J Transplant, 10; 1437-1444.
Ellis H, Calne RY and Watson CJE (2016) Lecture notes in general surgery. 13th Edition, Wiley, Oxford.
Areas of expertise
Liver, kidney, pancreas transplantation; organ preservation; donation after circulatory death; donor transmitted disease